• Publications
  • Influence
Potency, continence and complications in 3,477 consecutive radical retropubic prostatectomies.
PURPOSE We report results in a series of 3,477 consecutive patients treated with anatomical nerve sparing radical retropubic prostatectomy (RRP) in terms of recovery of erectile function, urinaryExpand
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Tumor size is associated with malignant potential in renal cell carcinoma cases.
PURPOSE We evaluated our experience with renal cortical tumors to determine whether tumor size is associated with malignant histology and/or nuclear grade. MATERIALS AND METHODS We identified 2,675Expand
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The toll-like receptor pathway: a novel mechanism of infection-induced carcinogenesis of prostate epithelial cells.
BACKGROUND Inflammation and infection have been linked to the pathogenesis of many cancers including prostate cancer. Components of bacteria and viruses have been identified within pathologicalExpand
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Prostate specific antigen density correlates with features of prostate cancer aggressiveness.
PURPOSE An increased prostate specific antigen density (serum prostate specific antigen divided by prostate volume) is an established parameter to help determine the need to perform prostateExpand
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Nuclear Factor-κB-Mediated Transforming Growth Factor-β-Induced Expression of Vimentin Is an Independent Predictor of Biochemical Recurrence after Radical Prostatectomy
  • Qiang Zhang, B. Helfand, +14 authors C. Lee
  • Medicine
  • Clinical Cancer Research
  • 15 May 2009
Purpose: Transforming growth factor-β (TGF-β)-mediated epithelial-to-mesenchymal transition (EMT) has been shown to occur in some cancers; however, the pathway remains controversial and varies withExpand
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Diagnostic Value of Guided Biopsies: Fusion and Cognitive-registration Magnetic Resonance Imaging Versus Conventional Ultrasound Biopsy of the Prostate.
OBJECTIVE To better assess the increased utilization of multiparametric magnetic resonance imaging (mpMRI) and fusion biopsy of the prostate, we compared prostate cancer detection rates among (a) menExpand
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National comparison of oncologic quality indicators between open and robotic-assisted radical cystectomy.
INTRODUCTION Despite increased adoption of robotic-assisted radical cystectomy (RARC), no national data have validated its oncologic efficacy compared to the "standard" open radical cystectomy (ORC).Expand
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Transforming growth factor-β in benign and malignant prostate
BACKGROUND The present review summarizes the cellular action of TGF-β in benign and malignant growth of the prostate. METHODS. TGF-β is a pleiotropic growth factor. It plays an importantExpand
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Preoperative PSA and progression-free survival after radical prostatectomy for Stage T1c disease.
OBJECTIVES To examine biochemical progression-free survival (PFS) rates as a function of preoperative prostate-specific antigen (PSA) in patients with clinical Stage T1c prostate cancer treated withExpand
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