S. Kumar

Publications45
h-index15
Citations740
Highly Influential Citations14
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Characterization of N- and O-linked glycosylation of recombinant human bile salt-stimulated lipase secreted by Pichia pastoris.
Recombinant human bile salt-stimulated lipase (hBSSL) was expressed in and secreted by Pichia pastoris, an organism exploited for the large-scale production of recombinant (glyco)proteins by… Expand
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Estrogen regulation of creatine kinase-B in the rat uterus.
Creatine kinase-B (CKB) synthesis is rapidly and specifically induced by estrogen in the uterus of the immature rat. This study indicates that this elevation is due at least in part to increases in… Expand
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3-INDOLEACETALDOXIME HYDRO-LYASE: A PYRIDOXAL-5'-PHOSPHATE ACTIVATED ENZYME.
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Estradiol preferentially enhances extracellular tissue plasminogen activators of MCF-7 breast cancer cells.
MCF-7 human breast cancer cells secrete two immunologic types of plasminogen activator, one related to urokinase, the other unrelated. We have now examined whether estrogen stimulation of secreted… Expand
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Suppression of estrogen-regulated extracellular tissue plasminogen activator activity of MCF-7 cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses the estrogen enhancement of tissue plasminogen activator (t-PA) by MCF-7 breast cancer cells. 17 beta-estradiol treatment of MCF-7 cells was… Expand
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Transcriptional regulation of surfactant proteins SP-A and SP-B by phorbol ester.
Phorbol esters such as 12-O-tetradecanoylphorbol-13-acetate (TPA) activate protein kinase C and have been previously shown to down-regulate surfactant proteins SP-A and SP-B in H441 adenocarcinoma… Expand
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Estrogen regulation of human breast cancer cell line MCF-7 tissue plasminogen activator.
The human breast cancer cell line MCF-7 produces a number of estrogen-regulated proteins, among which is tissue plasminogen activator (tPA). Increased medium concentrations of PA activity were… Expand
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Inhibition of Azotobacter vinelandii RNA polymerase by cibacron blue F3GA.
  • S. Kumar, J. Krakow
  • Medicine, Chemistry
  • The Journal of biological chemistry
  • 25 August 1977
Cibacron blue F3GA is a potent inhibitor of the Azotobacter vinelandii DNA-directed RNA polymerase. Addition of 8 micrometer Cibacron blue F3GA prior to initiation results in a greater than 90%… Expand
  • 25
Effect of Cibacron blue F3GA on oligonucleotide binding site of estradiol--receptor complexes of mouse uterine cytosol.
The binding of estradiol--receptor complexes of mouse uterine cytosol to oligodeoxynucleotide celluloses is inhibited by the sulfonated polyaromatic dye Cibacron blue F3GA. The dye does not have any… Expand
  • 15
Effect of chaotropic anions on the rate of dissociation of estradiol-receptor protein complexes of mouse uterine cytosol.
Abstract The stability of mouse uterine cytosol receptor-[ 3 H]estradiol complex was evaluated in the presence of neutral salts of the Hoffmeister series. Marked increases in the rate of dissociation… Expand
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