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Carbon-11-thymidine and FDG to measure therapy response.
TLDR
In this limited series, K(TdR) measurements showed a complete shutdown in tumor proliferation in patients in whom FDG showed a more limited decrease in glucose metabolism. Expand
Development of labeled thymidine analogs for imaging tumor proliferation.
TLDR
Of the three thymidine analogs tested, only FFUdR showed preferential retention in rapidly proliferating tissues, such as the spleen and implanted tumors, and it attained tissue to blood ratios of 2.1 at 2 h. Expand
Contribution of labeled carbon dioxide to PET imaging of carbon-11-labeled compounds.
TLDR
The data contradict the notion that the contribution of labeled CO2 to PET images can be disregarded because of its rapid elimination through the lungs and indicate that retention and distribution of labeledCO2 needs to be considered when interpreting PET data obtained from 11C-labeled compounds. Expand
Quantitative measurement of airway dimensions using ultra-high resolution computed tomography.
TLDR
The ultra-high resolution scan may allow more accurate measurement of the bronchioles with smaller dimensions compared with the conventional scan, and may resolve the smaller airway in COPD subjects. Expand
Feasibility and diagnostic performance of fractional flow reserve measurement derived from coronary computed tomography angiography in real clinical practice
TLDR
FFRCT could be measured in the majority of consecutive patients who had suspected significant CAD by CCTA in real clinical practice and demonstrated good diagnostic performance for detecting hemodynamically significant CAD even in patients with extremely severe calcified vessels. Expand
Radiosyntheses of labeled beta-pseudothymidine ([C-11]- and [H-3]methyl) and its biodistribution and metabolism in normal and tumored mice.
TLDR
Based on biodistribution and metabolite studies, the anticipated uptake of [H-3]methyl-beta-pseudothymidine into mouse DNA of proliferating tissues and implanted tumors was not observed and the method is simple and high specific activity tritiated methyl iodide can be used. Expand
Direct evaluation of peripheral airways using ultra-high-resolution CT in chronic obstructive pulmonary disease.
TLDR
U-HRCT enables accurate and direct evaluation of peripheral airways 1-2 mm in diameter, and the sum-LA can be a useful CT biomarker that reflects airflow limitation in COPD. Expand
Analysis of 2-carbon-11-thymidine blood metabolites in PET imaging.
TLDR
While it is essential to take metabolites into account when interpreting results obtained with 11C-thymidine, the reproducibility of these degradation curves may allow the use of a limited number of samples to measure the catabolic products of thymidine. Expand
Lobar distribution of non-emphysematous gas trapping and lung hyperinflation in chronic obstructive pulmonary disease.
TLDR
Non-emphysematous gas trapping in the upper and lower lobes has a distinct physiological effect, especially in COPD with minimal emphysema, and this local evaluation might allow sensitive detection of changes in lung hyperinflation in COPd. Expand
Internal evaluation of impregnation treatment of waterlogged wood; relation between concentration of internal materials and relaxation time using magnetic resonance imaging.
TLDR
Using visualization of relaxation time T1, it is possible to obtain more detail information noninvasively concerning the state of impregnation treatment of internal waterlogged wood. Expand
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