S. Koike

Publications178
h-index45
Citations9,064
Highly Influential Citations469
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Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste.
TLDR
Findings are discussed that address aspects of the fate, transport, and persistence of antibiotics and antibiotic resistance genes in natural environments, with emphasis on mechanisms pertaining to soil environments following land application of animal waste effluent.
Scavenger receptor B2 is a cellular receptor for enterovirus 71
TLDR
It is shown that human scavenger receptor class B, member 2 (SCARB2, also known as lysosomal integral membrane protein II or CD36b like-2) is a receptor for EV71, which supports the infection of the milder pathogen CVA16.
Rumen microbial community composition varies with diet and host, but a core microbiome is found across a wide geographical range
TLDR
There were few strong co-occurrence patterns between microbes, suggesting that major metabolic interactions are non-selective rather than specific, and could make it possible to mitigate methane emissions by developing strategies that target the few dominant methanogens.
Development and use of competitive PCR assays for the rumen cellulolytic bacteria: Fibrobacter succinogenes, Ruminococcus albus and Ruminococcus flavefaciens.
TLDR
Competitive PCR assays were developed for the enumeration of the rumen cellulolytic bacterial species: Fibrobacter succinogenes, R. albus and R. flavefaciens and the population size of the three species did not change after the proportion of dietary alfalfa hay was increased.
Molecular ecological analysis of the gastrointestinal microbiota: a review.
TLDR
A critical summary is provided of current molecular ecological approaches for studying the GI microbiota, such as those based on functional genes and their expression and the combined use of stable isotopes and biomarkers.
Six RNA Viruses and Forty-One Hosts: Viral Small RNAs and Modulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems
TLDR
Multiplexed high-throughput sequencing is used to characterize changes in small RNA populations that occur during viral infection in animal cells, defining vsRNAs as one possible component of the interplay between animal viruses and their hosts.
Monitoring and Source Tracking of Tetracycline Resistance Genes in Lagoons and Groundwater Adjacent to Swine Production Facilities over a 3-Year Period
TLDR
Antibiotic resistance genes in groundwater are affected by swine manure, but they are also part of the indigenous gene pool.
Erratum: Rumen microbial community composition varies with diet and host, but a core microbiome is found across a wide geographical range
TLDR
There were few strong co-occurrence patterns between microbes, suggesting that major metabolic interactions are non-selective rather than specific, and could make it possible to mitigate methane emissions by developing strategies that target the few dominant methanogens.
Kinetics of in sacco fiber-attachment of representative ruminal cellulolytic bacteria monitored by competitive PCR.
TLDR
F. succinogenes was most dominant, both in the whole rumen digesta and on the suspended hay stems, demonstrating the ecological and functional significance of this species in ruminal fiber digestion.
Transgenic mice susceptible to poliovirus.
  • S. Koike, C. Taya, A. Nomoto
  • Biology, Medicine
    Proceedings of the National Academy of Sciences…
  • 1 February 1991
TLDR
The transgenic mice may become an excellent new animal model to study molecular mechanisms of pathogenesis of poliov virus and to assess oral poliovirus vaccines.
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