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Promoter2.0: for the recognition of PolII promoter sequences
  • S. Knudsen
  • Biology, Computer Science
    Bioinform.
  • 1 May 1999
MOTIVATION A new approach to the prediction of eukaryotic PolII promoters from DNA sequence takes advantage of a combination of elements similar to neural networks and genetic algorithms to recognize…
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Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans.
TLDR
Combining RNA profiling with single-gene DNA marker association analysis yields a strongly validated molecular predictor with meaningful explanatory power for VO2max responses to endurance training.
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Improvement of Galactose Uptake in Saccharomyces cerevisiae through Overexpression of Phosphoglucomutase: Example of Transcript Analysis as a Tool in Inverse Metabolic Engineering
TLDR
It is concluded that phosphoglucomutase plays a key role in controlling the flux through the Leloir pathway, probably due to increased conversion of glucose-1-phosphate to glucose-6-ph phosphate in the strain construct overexpressing PGM2.
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Environmental DNA from Seawater Samples Correlate with Trawl Catches of Subarctic, Deepwater Fishes
TLDR
This study demonstrates that eDNA reads can be used as a qualitative and quantitative proxy for marine fish assemblages in deepwater oceanic habitats as well as to monitoring effects of ongoing climate change on marine biodiversity—especially in polar ecosystems.
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Design of oligonucleotides for microarrays and perspectives for design of multi-transcriptome arrays
TLDR
OligoWiz presents a set of parameter scores in a graphical interface to facilitate an overview for the user and presents an analysis of the limitations in designing oligonucleotide sets that can detect transcripts from multiple organisms.
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A checklist of the fish fauna of Greenland waters
TLDR
The opportunity of the International Polar Year 2007–08 is presented to present an updated check-list of the fishes of Greenland and discuss whether the growing diversity can be explained by global warming.
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Circulating microRNA expression profiles associated with systemic lupus erythematosus.
TLDR
Circulating miRNAs are systematically altered in SLE and suggest that circulating miRNA patterns distinguish SLE from other immunoinflammatory phenotypes.
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Reproducibility of Oligonucleotide Microarray Transcriptome Analyses
TLDR
A set of experiments to address intra- and interlaboratory reproducibility is highly relevant for application of DNA-microarray analysis in functional genomics and metabolic engineering and yielded over 95% agreement between the laboratories for transcripts that changed by over 2-fold, leaving only a small fraction of genes that exhibited laboratory bias.
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Comparison of capture and storage methods for aqueous macrobial eDNA using an optimized extraction protocol: advantage of enclosed filter
TLDR
Sterivex-GP filter capsule (originally designed for filtering micro-organisms) is recommended as an efficient capture method for sampling macrobial eDNA and reduced handling and less exposure to outside stress compared with other filters may contribute to better eDNA results.
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Molecular Networks of Human Muscle Adaptation to Exercise and Age
TLDR
It is concluded that human muscle age-related molecular processes appear distinct from the processes regulated by those of physical activity, as ATRA and AhR gene-sets appear to represent “generic” physical activity responsive gene-networks.
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