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Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids.
TLDR
Oleanolic acid was identified as an anti-HIV principle from several plants, including Rosa woodsii, Prosopis glandulosa, Phoradendron juniperinum, Syzygium claviflorum, and Hyptis capitata, and Ternstromia gymnanthera. Expand
Inhibitors of nitric oxide production from hops (Humulus lupulus L.).
TLDR
The inhibitory effect of extracts from Humulus lupulus L. on both the production of NO and the expression of inducible NO synthase (iNOS) in mouse macrophage RAW 2647 cells was investigated. Expand
Euphane and tirucallane triterpenes from the roots of Euphorbia kansui and their in vitro effects on the cell division of Xenopus.
TLDR
Four new euphane-type triterpenes were isolated from a 60% EtOH extract of Euphorbia kansui, together with alpha-euphol, and their structures were elucidated on the basis of extensive analysis of their 1D and 2D NMR spectral data. Expand
Inhibitory Effects of Constituents from Morus alba var. multicaulis on Differentiation of 3T3-L1 Cells and Nitric Oxide Production in RAW264.7 Cells
TLDR
The prenyl-flavonoids 11–14, 16, triterpenoids 17,18 and 20 showed significant inhibitory activity towards the differentiation of 3T3-L1 adipocytes. Expand
Inhibitory effect of citrus nobiletin on phorbol ester-induced skin inflammation, oxidative stress, and tumor promotion in mice.
TLDR
B nobiletin is a functionally novel and possible chemopreventive agent in inflammation-associated tumorigenesis and Nobiletin significantly inhibited two distinct stages of skin inflammation induced by double TPA application by decreasing the inflammatory parameters. Expand
Prenylflavonoids and phloroglucinol derivatives from hops (Humulus lupulus).
The ethyl acetate soluble fraction of hops (Humulus lupulus) showed potent inhibitory activity on the production of nitric oxide (NO) induced by a combination of LPS and IFN-gamma. Four knownExpand
Regulation and improvement of triterpene formation in plant cultured cells of Eriobotrya japonica Lindl.
TLDR
Various different culture conditions for cultured cells of loquat to produce triterpenes, including illumination, carbon source, nutrient composition and culture system are investigated, finding that suspension cultures of Loquat cell could achieve high productivity as callus culture. Expand
Inhibitory effect of stevioside on tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin.
Four steviol (ent-kaurene-type diterpenoid) glycosides, stevioside, rebaudiosides A and C, and dulcoside A, have been isolated from Stevia rebaudiana BERTONI. These compounds showed strong inhibitoryExpand
Diterpenes from the roots of Euphorbia kansui and their in vitro effects on the cell division of Xenopus.
TLDR
Of the three jatrophane diterpenes isolated from the roots of Euphorbia kansui, only kansuinin B (11) showed any activity, resulting in 87% cleavage arrest at 50 microg/mL. Expand
Inhibitory Effects of Constituents from Euphorbia lunulata on Differentiation of 3T3-L1 Cells and Nitric Oxide Production in RAW264.7 Cells
TLDR
Isolated hydrolysable tannins, flavonoids, and flavonol galactopyranoside gallates showed significant inhibition of the differentiation of 3T3-L1 preadipocytes and triglyceride accumulation in maturing adipocytes, and nitric oxide production in RAW 264.7 cells. Expand
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