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Comprehensive Polyadenylation Site Maps in Yeast and Human Reveal Pervasive Alternative Polyadenylation
The emerging discoveries on the link between polyadenylation and disease states underline the need to fully characterize genome-wide polyadenylation states. Here, we report comprehensive maps ofExpand
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Secondary structure of Huntingtin amino-terminal region.
Huntington's disease is a genetic neurodegenerative disorder resulting from polyglutamine (polyQ) expansion (>36Q) within the first exon of Huntingtin (Htt) protein. We applied X-ray crystallographyExpand
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Insulin resistance and C-reactive protein as independent risk factors for non-alcoholic fatty liver disease in non-obese Asian men.
BACKGROUND AND AIM Although insulin resistance is often considered the link between obesity and non-alcoholic fatty liver disease (NAFLD), the role of insulin resistance, independent of obesity, as aExpand
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Bocavirus Infection in Hospitalized Children, South Korea
This study presents the first evidence of human bocavirus infection in South Korean children. The virus was detected in 27 (8.0%) of 336 tested specimens, including 17 (7.5%) of 225 virus-negativeExpand
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Effect of carbon source and aeration rate on broth rheology and fungal morphology during red pigment production by Paecilomyces sinclairii in a batch bioreactor.
The influence of carbon source and aeration rate on fermentation broth rheology, mycelial morphology and red pigment production of Paecilomyces sinclairii was investigated in a 5-l stirred-tankExpand
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WU Polyomavirus in Children with Acute Lower Respiratory Tract Infections, South Korea
In South Korea, WU polyomavirus (WUPyV) was detected in 34 (7%) of 486 children with acute lower respiratory tract infections, 3 (4.2%) of 72 asymptomatic children, and as coinfection with otherExpand
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Submerged culture conditions for the production of mycelial biomass and exopolysaccharides by the edible Basidiomycete Grifola frondosa
Optimization of submerged culture conditions for mycelial biomass and exopolysaccharide (EPS) production by Grifola frondosa was studied. The optimal temperature and initial pH for both mycelialExpand
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The effect of topical bevacizumab on corneal neovascularization.
PURPOSE To examine the effect of topical bevacizumab on corneal neovascularization (NV) over a period of 3 months. DESIGN Prospective, nonrandomized, masked observational case series. Expand
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Optimization of submerged culture conditions for the mycelial growth and exo-biopolymer production by Cordyceps militaris.
AIMS The objective of the present study was to determine the optimal culture conditions for exo-biopolymer production by Cordyceps militaris in shake flask culture. METHODS AND RESULTS The optimalExpand
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An in-depth map of polyadenylation sites in cancer
We present a comprehensive map of over 1 million polyadenylation sites and quantify their usage in major cancers and tumor cell lines using direct RNA sequencing. We built the Expression andExpand
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