Share This Author
Zebrafish as a new model for phenotype-based screening of melanogenic regulatory compounds.
It is suggested that the zebrafish system is a novel alternative to mammalian models, with several advantages including the rapidity, cost-effectiveness, and physiological relevance, in screening and evaluating the putative melanogenic regulatory compounds.
Neuroprotective effects of the cyanidin-3-O-β-d-glucopyranoside isolated from mulberry fruit against cerebral ischemia
Dual Role of Inflammatory Stimuli in Activation-induced Cell Death of Mouse Microglial Cells
Evidence is presented that interferon regulatory factor-1 (IRF-1) and caspase-11 are the essential molecules in activation-induced cell death of microglial cells and that LPS/IFNγ not only induced the production of cytotoxic NO through IRf-1 but also initiated the NO-independent apoptotic pathway through the induction of casp enzyme-11.
Neurite outgrowth induced by spicatoside A, a steroidal saponin, via the tyrosine kinase A receptor pathway.
Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia
The results indicate that wogonin exerts its neuroprotective effect by inhibiting microglial activation, which is a critical component of pathogenic inflammatory responses in neurodegenerative diseases.
Chrysin suppresses LPS-stimulated proinflammatory responses by blocking NF-κB and JNK activations in microglia cells
Mulberry fruit protects dopaminergic neurons in toxin-induced Parkinson's disease models
Results indicate that ME has neuroprotective effects in in vitro and in vivo PD models, and that it may be useful in preventing or treating PD.
Inhibitory Effects of Resveratrol on Melanin Synthesis in Ultraviolet B-Induced Pigmentation in Guinea Pig Skin
This study is the first to provide evidence supporting resveratrol as a depigmentation agent, along with further clinical investigation of resver atrol in ultraviolet B-induced skin disorders such as hyperpigmentation and skin photoaging.
6-Shogaol, a ginger product, modulates neuroinflammation: A new approach to neuroprotection
Induction of caspase‐11 by inflammatory stimuli in rat astrocytes: lipopolysaccharide induction through p38 mitogen‐activated protein kinase pathway