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Genetic polymorphisms of IL-23R and IL-17A and novel insights into their associations with inflammatory bowel disease
Background and Aims To identify the associations of genetic and epigenetic variations in IL-23R and IL-17A with inflammatory bowel diseases (IBD). Methods The promoter and exon regions of IL-23R and… Expand
Neural Induction with Neurogenin 1 Enhances the Therapeutic Potential of Mesenchymal Stem Cells in an Amyotrophic Lateral Sclerosis Mouse Model
- Chan-Il Choi, Y. Lee, Heejaung Kim, S. Kim, H. Suh-Kim, S. Kim
- Cell transplantation
- 1 May 2013
Amyotrophic lateral sclerosis (ALS) is characterized by progressive dysfunction and degeneration of motor neurons in the central nervous system (CNS). In the absence of effective drug treatments for… Expand
New ent-kauranes from the fruits of Annona glabra and their inhibitory nitric oxide production in LPS-stimulated RAW264.7 macrophages.
- Nguyễn Xuân Nhiệm, Nguyen Dtn Hien, +10 authors Y. H. Kim
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 15 January 2015
Three new ent-kaurane diterpenoids, 7β,16α,17-trihydroxy-ent-kauran-19-oic acid (1), 7β,17-dihydroxy-16α-ent-kauran-19-oic acid 19-O-β-d-glucopyranoside ester (2),… Expand
Poor Prognosis of Lower Inner Quadrant in Lymph Node–negative Breast Cancer Patients Who Received No Chemotherapy: A Study Based on Nationwide Korean Breast Cancer Registry Database
Background We aimed to investigate the prognostic influence of primary tumor site on the survival of patients with breast cancer. Patients and Methods Data of 63,388 patients with primary breast… Expand
15-Deoxy-Δ12,14-Prostaglandin J2 Exerts Proresolving Effects Through Nuclear Factor E2-Related Factor 2-Induced Expression of CD36 and Heme Oxygenase-1.
AIMS 15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) has been shown to rescue cells from inflammatory insults and to participate in the resolution of acute inflammation. In this study, we investigated… Expand
Identification of a Novel p.Q1772X ANK1 Mutation in a Korean Family with Hereditary Spherocytosis
Hereditary spherocytosis (HS), a common form of inherited hemolytic anemia, is a heterogeneous group of disorders with regard to clinical severity, protein defects, and mode of inheritance. Causal… Expand
Oleanane-type saponins from Glochidion glomerulatum and their cytotoxic activities.
Eight oleanane-type saponins, glomerulosides A-H, were isolated from leaves of Glochidion glomerulatum. All isolated compounds were evaluated for cytotoxic activity on four human cancer cell lines,… Expand
Non-contact respiration monitoring using impulse radio ultrawideband radar in neonates
Vital sign monitoring in neonates requires adhesive electrodes, which often damage fragile newborn skin. Because impulse radio ultrawideband (IR-UWB) radar has been reported to recognize chest… Expand
Clinical utility of mono-exponential model diffusion weighted imaging using two b-values compared to the bi- or stretched exponential model for the diagnosis of biliary atresia in infant liver MRI
Purpose To investigate the clinical utility of mono-exponential model diffusion weighted imaging (DWI) using two b-values compared to the bi- or stretched exponential model to differentiate biliary… Expand
Nationwide Multicenter Study of Eosinophilic Esophagitis in Korean Children
- Kunsong Lee, B. Choe, +8 authors Hye Eun Yang
- Pediatric gastroenterology, hepatology…
- 1 May 2020
Purpose In East Asian countries, there are only a few epidemiologic studies of eosinophilic esophagitis (EoE) and no studies in children. We investigated the incidence and compared the clinical… Expand