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Properties of the gamma subunit of phosphorylase kinase.
  • S. Kee, D. Graves
  • Chemistry, Medicine
  • The Journal of biological chemistry
  • 15 July 1987
TLDR
Several protein substrates of holophosphorylase kinase were found also to be phosphorylated by the gamma subunit, including kappa-casein, myelin basic protein, the Troponin complex, and troponin T alone. Expand
Isolation and properties of the active gamma subunit of phosphorylase kinase.
  • S. Kee, D. Graves
  • Medicine, Chemistry
  • The Journal of biological chemistry
  • 5 April 1986
TLDR
A catalytically active gamma sub unit of phosphorylase kinase was prepared from pure, but inactive, gamma subunit obtained by reverse-phase high pressure liquid chromatography by substituting agarose-bound calmodulin for free Calmodulin in the reactivation procedure, and studies indicate that it may be equivalent to a gamma delta subunit complex previously isolated. Expand
Biochemical comparison of four commercially available human α1-proteinase inhibitors for treatment of α1-antitrypsin deficiency.
TLDR
This study compared the four plasma-derived α1-PI products commercially available in Europe by biochemical methods with respect to function, purity, structure, and chemical modifications to find Respreeza has the highest level of purity. Expand
Substrate specificity of phosphorylase kinase: effects of heparin and calcium.
TLDR
No indications were found for a stimulator-dependent specificity in the phosphorylation of sites in protein substrates of phosphorylase kinase (phosphorylases b, the alpha- and beta-subunits of phosphories, or glycogen synthase), which could not be explained by the different pH values at which the effects of the stimulators were assessed. Expand
Pathogen safety and characterisation of a highly purified human alpha1-proteinase inhibitor preparation.
TLDR
The purity and stability of Respreeza/Zemaira and the capacity of virus and prion reduction steps incorporated into its manufacturing process are described and taking into consideration the donor selection process, the testing of donations, and the highly effective virus andPrions reduction steps ensures the production of a stable and pure product. Expand
Isolation and properties of the catalytically active [gamma] subunit of phosphorylase kinase
TLDR
Studies of the reactivated r subunit in the presence of the reaction mixture indicate that this sample has properties similar to a y5 subunit complex, which is not significantly affected by pH within the range of pH 6.8 to pH 8.2. Expand
Purification and properties of branched-chain alpha-keto acid dehydrogenase kinase from bovine kidney.
TLDR
Branched-chain alpha-keto acid dehydrogenase (BCKDH) kinase was purified 5000-fold to apparent homogeneity from extracts of bovine kidney mitochondria and exhibited little activity, if any, toward pyruvate dehydrogen enzyme. Expand
Procédé de purification d'antitrypsine alpha-1
L'invention concerne un procede simplifie de purification d'antitrypsine alpha-1 (AAT) a partir d'un melange proteique contenant de l'AAT, tel qu'un precipite de fraction Cohn IV. Dans le procedeExpand
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