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Orchestrated transcription of key pathways in Arabidopsis by the circadian clock.
Like most organisms, plants have endogenous biological clocks that coordinate internal events with the external environment. We used high-density oligonucleotide microarrays to examine geneExpand
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Reciprocal Regulation Between TOC1 and LHY/CCA1 Within the Arabidopsis Circadian Clock
The interactive regulation between clock genes is central for oscillator function. Here, we show interactions between theArabidopsis clock genes LATE ELONGATED HYPOCOTYL(LHY), CIRCADIAN CLOCKExpand
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Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
In mammals, circadian control of physiology and behavior is driven by a master pacemaker located in the suprachiasmatic nuclei (SCN) of the hypothalamus. We have used gene expression profiling toExpand
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Overlapping and Distinct Roles of PRR7 and PRR9 in the Arabidopsis Circadian Clock
The core mechanism of the circadian oscillators described to date rely on transcriptional negative feedback loops with a delay between the negative and the positive components . In plants, the firstExpand
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The cryb Mutation Identifies Cryptochrome as a Circadian Photoreceptor in Drosophila
A new rhythm mutation was isolated based on its elimination of per-controlled luciferase cycling. Levels of period or timeless clock gene products in the mutant are flat in daily light-dark cycles orExpand
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The ELF4-ELF3-LUX Complex Links the Circadian Clock to Diurnal Control of Hypocotyl Growth
The circadian clock is required for adaptive responses to daily and seasonal changes in environmental conditions. Light and the circadian clock interact to consolidate the phase of hypocotyl cellExpand
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FKF1 and GIGANTEA Complex Formation Is Required for Day-Length Measurement in Arabidopsis
Precise timing of CONSTANS (CO) gene expression is necessary for day-length discrimination for photoperiodic flowering. The FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1), and GIGANTEA (GI) proteinsExpand
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Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim.
The circadian oscillator generates a rhythmic output with a period of about 24 hours. Despite extensive studies in several model systems, the biochemical mode of action has not yet been demonstratedExpand
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FKF1 F-Box Protein Mediates Cyclic Degradation of a Repressor of CONSTANS in Arabidopsis
The temporal control of CONSTANS (CO) expression and activity is a key mechanism in photoperiodic flowering in Arabidopsis. FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1) protein regulates COExpand
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Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog.
The toc1 mutation causes shortened circadian rhythms in light-grown Arabidopsis plants. Here, we report the same toc1 effect in the absence of light input to the clock. We also show that TOC1Expand
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