Antiproliferative activity of flavonoids on several cancer cell lines.
- S. Kawaii, Y. Tomono, E. Katase, K. Ogawa, M. Yano
- ChemistryBioscience, biotechnology and biochemistry
- 1999
The structure-activity relationship established from comparison among these flavones and flavanones showed that the ortho-catechol moiety in ring B and a C2-C3 double bond were important for the antiproliferative activity of these flavonoids.
Quantitation of flavonoid constituents in citrus fruits.
- S. Kawaii, Y. Tomono, E. Katase, K. Ogawa, M. Yano
- Biology, MedicineJournal of Agricultural and Food Chemistry
- 5 August 1999
Principal component analysis revealed that the distributions of Citrus species belonging to different classes were largely in accordance with Tanaka's classification system.
HL-60 differentiating activity and flavonoid content of the readily extractable fraction prepared from citrus juices.
- S. Kawaii, Y. Tomono, E. Katase, K. Ogawa, M. Yano
- Medicine, ChemistryJournal of Agricultural and Food Chemistry
- 1999
Principal component and cluster analyses of the readily extractable flavonoids indicated peculiarities of King and Bergamot.
Serotonin involvement in larval settlement of the barnacle, Balanus amphitrite
- Hisashi Yamamoto, A. Tachibana, S. Kawaii, K. Matsumura, N. Fusetani
- Biology
- 1 August 1996
Results suggest that serotonin is involved in larval settlement, and that cyprids exposed to neurotransmitters exposed to these uptake blockers metamorphosed without settling on substrata.
Differentiation-promoting activity of pomegranate (Punica granatum) fruit extracts in HL-60 human promyelocytic leukemia cells.
The results highlight an important, previously unknown, mechanism of the cancer preventive and suppressive potential of pomegranate fermented juice and pericarp extracts.
1,1-Diphenyl-2-picrylhydrazyl Radical-scavenging Compounds from Soybean Miso and Antiproliferative Activity of Isoflavones from Soybean Miso toward the Cancer Cell Lines
- A. Hirota, Shoji TAKi, S. Kawaii, M. Yano, N. Abe
- Medicine, ChemistryBioscience, biotechnology and biochemistry
- 1 January 2000
8-hydroxydaidzein, 8-hydroxygenistein and syringic acid had as high DPPH radical-scavenging activity as that of α-tocopherol as well as four of the isolated isoflavones toward three cancer cell lines.
Isolation of 8-Hydroxyglycitein and 6-Hydroxydaidzein from Soybean Miso
- A. Hirota, Miyuki Inaba, S. Kawaii
- Chemistry, MedicineBioscience, biotechnology and biochemistry
- 1 January 2004
We isolated from soybean miso 8-hydroxyglycitein and 6-hydroxydaidzein as DPPH-radical scavengers, and elucidated their chemical structures by mass spectrometric, and 1H- and 13C-NMR spectrosopic…
The antiproliferative effect of coumarins on several cancer cell lines.
- S. Kawaii, Y. Tomono, K. Ogawa, M. Sugiura, M. Yano, Y. Yoshizawa
- Biology, ChemistryAnticancer Research
- 1 March 2001
Analysis of cell cycle distribution indicated that esculetin-treated cells accumulated in the G1 or in S phase of the cell cycle, indicating that the 6,7-dihydroxy moiety had an important role for their antiproliferative activity.
Quantitative study of flavonoids in leaves of citrus plants.
- S. Kawaii, Y. Tomono, H. Furukawa
- Biology, MedicineJournal of Agricultural and Food Chemistry
- 9 August 2000
Leaf flavonoids were quantitatively determined in 68 representative or economically important Citrus species, cultivars, and near-Citrus relatives and revealed that the 7 associations according to Tanaka's classification were observed, but some do overlap each other.
Effect of coumarins on HL-60 cell differentiation.
The structure-activity relationship established from the results revealed that 6,7-dihydroxy moiety had an important role in the induction of differentiation of HL-60.
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