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Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo
Studies on the burden of human monkeypox in the Democratic Republic of the Congo (DRC) were last conducted from 1981 to 1986. Since then, the population that is immunologically naïve toExpand
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Genomic Variability of Monkeypox Virus among Humans, Democratic Republic of the Congo
Health authorities should be vigilant for this rapidly evolving virus.
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Using Remote Sensing to Map the Risk of Human Monkeypox Virus in the Congo Basin
Although the incidence of human monkeypox has greatly increased in Central Africa over the last decade, resources for surveillance remain extremely limited. We conducted a geospatial analysis usingExpand
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Experimental Aerosolized Guinea Pig–Adapted Zaire Ebolavirus (Variant
Eight guinea pigs were aerosolized with guinea pig–adapted Zaire ebolavirus (variant: Mayinga) and developed lethal interstitial pneumonia that was distinct from lesions described in guinea pigsExpand
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Pathogen-Host Associations and Predicted Range Shifts of Human Monkeypox in Response to Climate Change in Central Africa
Climate change is predicted to result in changes in the geographic ranges and local prevalence of infectious diseases, either through direct effects on the pathogen, or indirectly through rangeExpand
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In vitro inhibition of monkeypox virus production and spread by Interferon-β
BackgroundThe Orthopoxvirus genus contains numerous virus species that are capable of causing disease in humans, including variola virus (the etiological agent of smallpox), monkeypox virus, cowpoxExpand
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Dose Response of MARV/Angola Infection in Cynomolgus Macaques following IM or Aerosol Exposure
Marburg virus infection in humans causes a hemorrhagic disease with a high case fatality rate. Countermeasure development requires the use of well-characterized animal models that mimic humanExpand
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Detailed Analysis of the African Green Monkey Model of Nipah Virus Disease
Henipaviruses are implicated in severe and frequently fatal pneumonia and encephalitis in humans. There are no approved vaccines or treatments available for human use, and testing of candidatesExpand
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Smallpox vaccine, ACAM2000: Sites and duration of viral shedding and effect of povidone iodine on scarification site shedding and immune response.
The U.S. Department of Defense vaccinates personnel deployed to high-risk areas with the vaccinia virus (VACV)-based smallpox vaccine. Autoinoculations and secondary and tertiary transmissions due toExpand
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Attenuation and efficacy of live-attenuated Rift Valley fever virus vaccine candidates in non-human primates
Rift Valley fever virus (RVFV) is an important mosquito-borne veterinary and human pathogen that has caused large outbreaks of severe disease throughout Africa and the Arabian Peninsula. Currently,Expand
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