• Publications
  • Influence
Progressive histopathological changes in pancreatic islets of Zucker Diabetic Fatty rats.
Thus far, histopathological changes in the pancreatic islets of Zucker Diabetic Fatty (ZDF) rats, an animal model of type 2 diabetes mellitus (or non-insulin-dependent diabetes mellitus), have onlyExpand
  • 37
  • 3
Student Attitudes and Approaches to Online Homework
Over the past two decades there has been increasing movement toward the use of computers and the internet in conjunction with many courses across the educational spectrum. In addition to havingExpand
  • 40
  • 3
  • PDF
Alternatively spliced forms of the human myeloid Fcα receptor (CD89) in neutrophils
The human IgA Fc receptor (CD89) is a transmembrane glycoprotein expressed on cells of the myeloid lineage and proposedly plays a significant role in immunity_ Binding of IgA-opsonized targets toExpand
  • 34
  • 2
In Zucker diabetic fatty rats plasma leptin levels are correlated with plasma insulin levels rather than with body weight.
The obese (ob) gene product leptin, secreted from adipose tissue, acts in the hypothalamus to regulate body energy stores. In vitro experiments showed that insulin increases both leptin mRNAExpand
  • 19
  • 1
The ethmoidal region of the skull of Ptilocercus lowii (Ptilocercidae, Scandentia, Mammalia) – a contribution to the reconstruction of the cranial morphotype of primates
Abstract. The ethmoidal region of the skull houses one of the most important sense organs of mammals, the sense of smell. Investigation of the ontogeny and comparative anatomy of internal nasalExpand
  • 4
  • 1
  • PDF
Active Learning in Large Introductory Sociology Courses.
The method of teaching introductory sociology courses has been debated over the past 20 years. The standard lecture format for large (200 plus students) introductory courses has been criticized and aExpand
  • 46
  • 1
Expression of the Novel Epithelial Ca2+ Channel ECaC1 in Rat Pancreatic Islets
The epithelial Ca2+ channel, ECaC1, is primarily expressed in the apical membrane of vitamin D-responsive tissues. This study characterizes for the first time the presence of this novel channel inExpand
  • 28
Phlorizin treatment prevents the decrease in plasma insulin levels but not the progressive histopathological changes in the pancreatic islets during aging of Zucker diabetic fatty rats
A hallmark of Type 2 diabetes mellitus (T2DM) is chronic hyperglycemia, which is thought to play a role in pancreatic β-cell failure. Here we investigated whether treatment of Zucker diabetic fattyExpand
  • 20
Non-Publication Is Common among Phase 1, Single-Center, Not Prospectively Registered, or Early Terminated Clinical Drug Trials
The objective of this study was to investigate the occurrence and determinants of non-publication of clinical drug trials in the Netherlands.All clinical drug trials reviewed by the 28 InstitutionalExpand
  • 9
  • PDF