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Progressive histopathological changes in pancreatic islets of Zucker Diabetic Fatty rats.
Thus far, histopathological changes in the pancreatic islets of Zucker Diabetic Fatty (ZDF) rats, an animal model of type 2 diabetes mellitus (or non-insulin-dependent diabetes mellitus), have only… Expand
Student Attitudes and Approaches to Online Homework
Over the past two decades there has been increasing movement toward the use of computers and the internet in conjunction with many courses across the educational spectrum. In addition to having… Expand
Alternatively spliced forms of the human myeloid Fcα receptor (CD89) in neutrophils
The human IgA Fc receptor (CD89) is a transmembrane glycoprotein expressed on cells of the myeloid lineage and proposedly plays a significant role in immunity_ Binding of IgA-opsonized targets to… Expand
In Zucker diabetic fatty rats plasma leptin levels are correlated with plasma insulin levels rather than with body weight.
- S. Janssen, G. Martens, C. Sweep, H. Ross, A. Hermus
- Medicine, Biology
- Hormone and metabolic research = Hormon- und…
- 1 November 1999
The obese (ob) gene product leptin, secreted from adipose tissue, acts in the hypothalamus to regulate body energy stores. In vitro experiments showed that insulin increases both leptin mRNA… Expand
The ethmoidal region of the skull of Ptilocercus lowii (Ptilocercidae, Scandentia, Mammalia) – a contribution to the reconstruction of the cranial morphotype of primates
Abstract. The ethmoidal region of the skull houses one of the most important sense organs of mammals, the sense of smell. Investigation of the ontogeny and comparative anatomy of internal nasal… Expand
Active Learning in Large Introductory Sociology Courses.
The method of teaching introductory sociology courses has been debated over the past 20 years. The standard lecture format for large (200 plus students) introductory courses has been criticized and a… Expand
Expression of the Novel Epithelial Ca2+ Channel ECaC1 in Rat Pancreatic Islets
- S. Janssen, J. Hoenderop, A. Hermus, F. Sweep, G. Martens, R. Bindels
- Medicine, Biology
- The journal of histochemistry and cytochemistry…
- 1 June 2002
The epithelial Ca2+ channel, ECaC1, is primarily expressed in the apical membrane of vitamin D-responsive tissues. This study characterizes for the first time the presence of this novel channel in… Expand
Phlorizin treatment prevents the decrease in plasma insulin levels but not the progressive histopathological changes in the pancreatic islets during aging of Zucker diabetic fatty rats
- S. Janssen, G. Martens, C. Sweep, P. Span, A. Verhofstad, A. Hermus
- Journal of endocrinological investigation
- 1 June 2003
A hallmark of Type 2 diabetes mellitus (T2DM) is chronic hyperglycemia, which is thought to play a role in pancreatic β-cell failure. Here we investigated whether treatment of Zucker diabetic fatty… Expand
Alternatively spliced forms of the human myeloid Fc alpha receptor (CD89) in neutrophils.
Non-Publication Is Common among Phase 1, Single-Center, Not Prospectively Registered, or Early Terminated Clinical Drug Trials
The objective of this study was to investigate the occurrence and determinants of non-publication of clinical drug trials in the Netherlands.All clinical drug trials reviewed by the 28 Institutional… Expand