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Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1).
Data demonstrate that the skin is in fact a steroidogenic tissue and the clinical significance of this finding in mediating androgenic skin disorders such as acne, hirsutism, or androgenetic alopecia remains to be established.
Stromal cells of the human postmenopausal ovary display a distinctive biochemical and molecular phenotype.
It is concluded that the predominant stromal cells of the postmenopausal ovary are not a significant site of androgen biosynthesis, and these cells do not appear to have significant steroidogenic potential in vitro, but they do metabolize cholesterol into hydroxysterols.
Citalopram in PMS patients with prior SSRI treatment failure: a preliminary study.
Results from a small number of subjects with open-label treatment suggest that citalopram treatment is effective for PMS patients who failed previous SSRI treatment, and all DSR factor scores significantly improved.
Is Rh immune globulin needed in early first-trimester abortion? A review.
The existing medical literature is reviewed to assess the risks of fetomaternal hemorrhage and Rh isoimmunization after complications of a first-trimester pregnancy, induced abortion, or ectopic pregnancy.
A comparison of live birth rates and perinatal outcomes between cryopreserved oocytes and cryopreserved embryos
  • J. Ho, I. Woo, K. Chung
  • Medicine, Biology
    Journal of Assisted Reproduction and Genetics
  • 17 July 2017
Live birth rates and perinatal outcomes were not significantly different in patients after oocyte and embryo cryopreservation, and the mean age was lower in the FOET vs FET group, but there were no differences in ovarian reserve markers.
In vitro fertilization in the PCOS patient: clinical considerations.
Of all the patients undergoing in vitro fertilization, the patient with polycystic ovary syndrome (PCOS) is probably the most challenging. This is due to the fact that the majority of patients
Developmentally delayed cleavage-stage embryos maintain comparable implantation rates in frozen embryo transfers
Despite a higher prevalence of diminished ovarian reserve in the day 4 group, delayed cleavage-stage embryos utilized in FET cycles performed as well as embryos growing at the normal rate, suggesting delayed embryo development does not affect embryo implantation as long as endometrial synchrony is maintained.