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Establishment of a feline T-lymphoblastoid cell line highly sensitive for replication of feline immunodeficiency virus
Interleukin-2 dependent feline T-lymphoblastoid cells designated as MYA-1 cells were established, free from exogenous retroviruses and sensitive for replication of feline immunodeficiency virus (FIV). Expand
Molecular cloning and characterization of a new member of the rat placental prolactin (PRL) family, PRL-like protein D (PLP-D).
Sequence comparison between PLP-D and other members of the placental PRL family showed that PLp-D is highly homologous toPLP-C (80%) and decidual PRL-related protein (73%) and its expression increased until term. Expand
Possible role of macrophage-derived soluble mediators in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice
It is concluded that macrophage-produced soluble mediators play an important role in the destruction of pancreatic beta cells, resulting in the development of diabetes in mice infected with a low dose of EMC-D virus. Expand
Age-related changes in major lymphocyte subsets in cynomolgus monkeys.
The results indicated that the age-related changes in percentages of major lymphocyte subsets as well as in phenotypes of T cells might be related to the maturation of the immune system including an increase in memory cells in cynomolgus monkeys. Expand
20α-Hydroxysteroid dehydrogenase activity in rat placenta
The hypothesis that 20α-HSD acts as a survival factor for fetuses, protecting them from the cytotoxic activity of progesterone by metabolizing it to the inactive steroid is supported. Expand
Depletion of Mac1-positive macrophages protects DBA/2 mice from encephalomyocarditis virus-induced myocarditis and diabetes.
DBA/2 mice treated with anti-Mac1 monoclonal antibody (MAb) failed to develop encephalomyocarditis virus (EMCV)-induced diabetes and myocarditis and Mac1-positive macrophages seem to be involved in EMCV-induced disease and to affect the replication of E MCV in target organs. Expand
Relation between distribution of viral RNA and development of histopathological changes in encephalomyocarditis virus‐induced orchitis in mice
The results suggest that EMC virus carried to seminiferous tubules via the blood first attacks Sertoli cells and then damages germinal cells and spermatogonia. Expand
Hepatic changes of mice in the subacute phase of streptozotocin (SZ)-induced diabetes.
Hepatic changes of mice in the subacute phase of streptozotocin (SZ)-induced diabetes were investigated biochemically and pathologically and in some SZ-induced diabetic mice, bile duct hyperplasia with an appearance of cytomegalic hepatocytes was observed. Expand
Preliminary comparisons of the biological properties of two strains of feline immunodeficiency virus (FIV) isolated in Japan with FIV Petaluma strain isolated in the United States
SummaryTwo strains of feline immunodeficiency virus (FIV) were isolated directly from peripheral blood mononuclear cells (PBMCs) of Japanese domestic cats or indirectly from PBMCs of specificExpand
Histopathology of subacute renal lesions in mice induced by streptozotocin.
Streptozotocin was inoculated intraperitoneally to male and female mice of ICR and BALB/c strains in a different way of administration and subacute renal changes were examined light and electron microscopically 8 weeks after SZ-administration. Expand