• Publications
  • Influence
Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan
Recent studies revealed that a substantial proportion of patients with high-risk B-cell precursor acute lymphoblastic leukemia (BCP-ALL) harbor fusions involving tyrosine kinase and cytokineExpand
  • 42
  • 2
Promoter polymorphism in the macrophage migration inhibitory factor gene is associated with obesity
Objective:To explore the association of promoter polymorphisms of macrophage migration inhibitory factor (MIF) gene with obesity.Subjects:In total, 213 nondiabetic Japanese subjects. They wereExpand
  • 25
Factors associated with posttraumatic growth among parents of children with cancer
Parents of children with cancer are susceptible to psychological distress; however, many parents also report posttraumatic growth (PTG). The objective of this study was to explore the variablesExpand
  • 7
Evaluation of aprepitant and fosaprepitant in pediatric patients
Single‐dose i.v. fosaprepitant has been approved as an alternative to 3 day oral aprepitant, a neurokinin‐1 receptor antagonist, and improves prevention of chemotherapy‐induced nausea and vomitingExpand
  • 6
A case of recurrent histiocytic sarcoma with MAP2K1 pathogenic variant treated with the MEK inhibitor trametinib
Histiocytic sarcoma in advanced clinical stages is typically an aggressive neoplasm, with poor response to conventional chemotherapy. An 18-year-old male with refractory histiocytic sarcoma that hadExpand
  • 6
Effect of UGT2B17 deletion polymorphism on prognosis in pediatric cancer
UDP‐glucuronosyltransferase 2 family, polypeptide B17 (UGT2B17) encodes for an enzyme that modifies carcinogens, C19 steroids, xenobiotics, and anticancer chemotherapeutic agents by glucuronidation.Expand
  • 2
First report of an Asian family with hemoglobin Evans [α2 62 (E11) Val → Met]
Hemoglobin Evans is an unstable variant caused by a single nucleotide mutation that produces a valine‐to‐methionine substitution at residue 62 of the α‐globin chain. It has not been reported in theExpand
  • 1
The Association Between L-Asparaginase Hypersensitivity and Genetic Variants in Japanese Childhood ALL Patients
Background L-asparaginase is important in successfully treating childhood acute lymphoblastic leukemia (ALL). However, some patients experience hypersensitivity, mechanisms for which have not beenExpand
  • 2
Nationwide study of pediatric B‐cell precursor acute lymphoblastic leukemia with chromosome 8q24/MYC rearrangement in Japan
Rearrangements of chromosome 8q24/MYC (8q24/MYC‐r), resulting from t(8;14)(q24;q32), t(2;8)(p11;q24), or t(8;22)(q24;q11), are mainly associated with Burkitt lymphoma/leukemia (BL) and rarelyExpand
[Successful treatment of very severe late-onset sinusoidal obstruction syndrome with recombinant human soluble thrombomodulin, steroids, and control of intra-abdominal pressure].
We report a case of a 16-year-old woman who achieved her third complete remission of acute lymphoblastic leukemia after undergoing allogeneic stem cell transplantation for the second time from anExpand