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Structural basis for the carbohydrate recognition of the Sclerotium rolfsii lectin.
Sequence and structural comparisons reveal that SRL is the third member of a newly identified family of fungal lectins, which includes lectins from Agaricus bisporus and Xerocomus chrysenteron that share a high degree of structural similarity and carbohydrate specificity.
Immunolocalization and functional role of Sclerotium rolfsii lectin in development of fungus by interaction with its endogenous receptor.
The importance of lectin-receptor interactions to explain hitherto speculated functional role of the lectins and also the glycosphingolipids of fungi is demonstrated.
Purification, characterization and molecular cloning of a monocot mannose-binding lectin from Remusatia vivipara with nematicidal activity
Very high mortality rate was observed at lectin concentration as low as 30 µg/ml, suggesting its potential application in the development of nematode resistant transgenic-crops.
A potent mitogenic lectin from the mycelia of a phytopathogenic fungus, Rhizoctonia bataticola, with complex sugar specificity and cytotoxic effect on human ovarian cancer cells
A lectin with strong mitogenic activity towards human peripheral blood mononuclear cells (PBMCs) and cytotoxic effect on human ovarian cancer cells has been purified from the mycelium of a
Crystal structure of a β-prism II lectin from Remusatia vivipara.
Apart from being the first structure of a lectin to be reported from the Araceae/Arum family, this protein also displays a novel mode of oligomerization among BP2 lectins.
Carbohydrate specificity of a lectin isolated from the fungus Sclerotium rolfsii.
It is suggested that T(alpha) and Tn glycotopes, which are present only in abnormal carbohydrate sequences of higher orders of mammal, are the most likely sites for phytopathogenic fungal attachment as an initial step of infection.
Rhizoctonia bataticola lectin (RBL) induces mitogenesis and cytokine production in human PBMC via p38 MAPK and STAT-5 signaling pathways.
RBL-induced proliferation and production of Th1/Th2 cytokines are mediated via p38 MAPK and STAT-5 signaling and the results identified the signaling mechanism underlying the immunostimulatory activity of RBL.
Purification, characterization and biological significance of mannose binding lectin from Dioscorea bulbifera bulbils.
Glycan array analysis of DBL revealed its affinity toward high mannose N-linked glycans with enhanced affinity for terminalMannose including N- linked glycans of HIV envelope glycoprotein gp120 and has strong anti-reverse transcriptase activity.
Pharmacokinetics, biodistribution and antitumour effects of Sclerotium rolfsii lectin in mice.
Sclerotium rolfsii lectin has good potential to be developed as a therapeutic agent for cancer treatment and warrant further investigations in vivo and subsequent clinical trials.
High mannose N-glycan binding lectin from Remusatia vivipara (RVL) limits cell growth, motility and invasiveness of human breast cancer cells.
The potential of Remusatia vivipara lectin (RVL), inducing apoptosis in breast cancer cells there by limiting motility and invasiveness is described, resulting in curtailing the metastatic ability of cancer cells.