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- Publications
- Influence
Analgesic effect of morphine glucuronides.
- K. Shimomura, O. Kamata, +4 authors H. Tsukamoto
- Chemistry, Medicine
- The Tohoku journal of experimental medicine
- 1 September 1971
Pharmacological properties of morphine-3-glucuronide and morphine-6-glucuronide were studied in mice and compared with those of morphine. 1) The analgesic effect of morphine-6-glucuronide was 3 to 4… Expand
Biochemical basis for analgesic activity of morphine-6-glucuronide. I. Penetration of morphine-6-glucuronide in the brain of rats.
- H. Yoshimura, S. Ida, K. Oguri, H. Tsukamoto
- Chemistry, Medicine
- Biochemical pharmacology
- 15 June 1973
Abstract To understand the potent analgesic action of morphine-6-glucuronide (M-6-G), which was reported previously to be a minor metabolite of morphine in several mammalian species, the penetration… Expand
Monoallelic expression of normal mRNA in the PIT1 mutation heterozygotes with normal phenotype and biallelic expression in the abnormal phenotype.
- N. Okamoto, Y. Wada, +5 authors K. Tatsumi
- Biology, Medicine
- Human molecular genetics
- 1 September 1994
The combined deficiency of thyrotropin, growth hormone and prolactin, caused by PIT1 abnormality manifests in the homozygous or heterozygous state. We studied a patient having an allele with… Expand
Mast cells in bronchoalveolar lumen of patients with bronchial asthma.
- M. Tomioka, S. Ida, Y. Shindoh, T. Ishihara, T. Takishima
- Medicine
- The American review of respiratory disease
- 1 June 1984
Bronchoalveolar lavage was performed on patients with stable bronchial asthma to elucidate the existence and significance of mast cells in human bronchoalveolar lumen. The percentage of total mast… Expand
Excretion of porphyrins in urine and bile after the administration of delta-aminolevulinic acid.
- Y. Shimizu, S. Ida, H. Naruto, G. Urata
- Chemistry, Medicine
- The Journal of laboratory and clinical medicine
- 1 November 1978
Excretion of porphyrins into bile and urine after intravenous injection of delta-ALA was studied in three patients with catheters inserted into the bile duct because of biliary obstruction and in two… Expand
Specificity of anti-nuclear antibodies induced in F1 mice undergoing the graft-vs-host reaction: isotypes and cross-reactivities.
- M. Kimura, S. Ida, K. Shimada, Yoshiyuki Kanai
- Chemistry, Medicine
- Clinical and experimental immunology
- 1 August 1987
(C57BL/6 X DBA/2)F1 mice undergoing the graft-vs-host reaction (GVHR) produce autoantibodies after the injection of DBA/2 lymphoid cells. The anti-nuclear antibodies, including anti-poly (ADP-ribose)… Expand
Metabolism of drugs. LXIX. Studies on the urinary metabolites of morphine in several mammlian species.
- K. Oguri, S. Ida, H. Yoshimura, H. Tsukamoto
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 25 December 1970
In the previous study of this series, morphine was shown to be metabolized not only to morphine-3-glucuronide, but also to morphine-6-glucuronide in rabbits. The present study have demonstrated that… Expand
Erythromycin increases bactericidal activity of surface liquid in human airway epithelial cells.
- Kota Ishizawa, T. Suzuki, +6 authors H. Sasaki
- Biology, Medicine
- American journal of physiology. Lung cellular and…
- 1 October 2005
Macrolide antibiotics have clinical benefits in patients with diffuse panbronchiolitis and in patients with cystic fibrosis. Although many mechanisms have been proposed, the precise mechanisms are… Expand
In vivo antiviral effects of mismatched double‐stranded RNA on duck hepatitis B virus
- K. Ijichi, K. Mitamura, S. Ida, H. Machida, K. Shimada
- Biology, Medicine
- Journal of medical virology
- 1 June 1994
The antiviral activity and ability of mismatched double‐stranded RNA (m‐dsRNA), r(I)n′r(C12‐U)n′ to induce interferon (IFN) were evaluated in ducks chronically infected with duck hepatitis B virus… Expand
Effects of Lithium on the Pharmacokinetics of Valproate in Rats
- H. Yoshioka, S. Ida, +4 authors Y. Takiguchi
- Chemistry, Medicine
- The Journal of pharmacy and pharmacology
- 1 March 2000
Combined treatment with lithium and valproate has been used for bipolar disorder. However, the studied interaction between these two drugs has not been fully investigated. We therefore examined the… Expand