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A microbiologic method for detecting folic acid deficiency in man.
Comparison with formimino-L-glutamic acid determinations and other microbiologic assay methods shows the assay here described to yield a more dependable estimate of the folic acid status in humans. Expand
Polyamine metabolism: a potential therapeutic target in trypanosomes.
alpha-Difluoromethylornithine (RMI 71,782), a specific irreversible inhibitor of the first step in polyamine biosynthesis, cures mice infected with a virulent, rodent-passaged strain of Trypanosoma brucei bruceo, drawing attention to polyamine metabolism as a target for chemotherapy of parasitic diseases. Expand
A mathematical model of pattern formation by swimming microorganisms.
A mathematical model describing the hydrodynamics of suspension of negatively geotactic microorganisms is described which predicts the existence of critical depths and concentrations and solutions describing the "polka-dot" patterns seen at low organism concentration in suspensions slightly deeper than the critical value are presented. Expand
A Sugar‐Containing Basal Medium for Vitamin B12‐Assay with Euglena; Application to Body Fluids*
The z strain of Euglena gracilis, which grows more vigorously than the bacillaris strain previously used, is recommended and allows the distinction between “combined” and “uncomb combined” B12 in serum. Expand
Biochemistry and physiology of protozoa.
Biochemistry and physiology of protozoa is studied in detail in order to clarify the role of “cell reprograming” in the “building blocks” of disease. Expand
Chapter 8 Culture Media for Euglena gracilispter1
High-yield media and how to compound media as dry mixes, which may be prepared cheaply in bulk and have a long shelf life are emphasized, as inquiries increasingly revolve around trace constituents and large quantities of cells are often needed. Expand
A practical assay of lipoate in biologic fluids and liver in health and disease.
With this practical assay, it is now possible to chart lipoate's antioxidant activity and therapeutic action during health and disease. Expand
No group offers more diverse and numerous species for the study of the comparative biochemical evolution of parasitism than does the Trypanosomidae. Unfortunately, little biochemical study of thisExpand