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NMR relaxation times in the human brain at 3.0 tesla
Relaxation time measurements at 3.0 T are reported for both gray and white matter in normal human brain in normal adults with no clinical evidence of neurological disease, and there were no significant differences in T1 from one location in the brain to another. Expand
Normal fMRI Brain Activation Patterns in Children Performing a Verb Generation Task
Although much is known concerning brain-language relations in adults, little is known about how these functions might be represented during the developmental period. We report results from 17 normalExpand
Correlation of white matter diffusivity and anisotropy with age during childhood and adolescence: a cross-sectional diffusion-tensor MR imaging study.
Diffusion-tensor MR imaging results indicate that white matter maturation assessed at different ages involves increases in both white matter density and organization during childhood and adolescence. Expand
Bright spots: correlations of gray matter volume with IQ in a normal pediatric population
Volumetric, voxel-based, and structural connectivity analyses to magnetic resonance images from a large sample of healthy children confirmed a strong correlation of whole-brain gray matter volume and the individual intelligence quotient, and the anterior cingulate was shown to be directly correlated with a measure of human intelligence. Expand
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy.
It is suggested that ischemia-hypoxia is a powerful stimulus for spontaneous coagulation leading to reperfusion deficits and autophagic/lysosomal cell death in brain. Expand
fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder.
The results in unmedicated patients are consistent with those from previous studies with medicated patients and suggest that OCD symptomatology is mediated by multiple brain regions including the anterior cingulate as well as frontal and temporal brain regions. Expand
Template-O-Matic: A toolbox for creating customized pediatric templates
A new, and generalized method of constructing appropriate reference data by statistically analyzing a large sample of healthy children, as acquired during the NIH MRI study of normal brain development, is described, which is implemented in the form of a toolbox for the SPM5 image data processing suite, which the authors term Template-O-Matic. Expand
Diffusion Tensor MR Imaging Reveals Persistent White Matter Alteration after Traumatic Brain Injury Experienced during Early Childhood
Evidence that WM integrity remains abnormal in children with moderate-to-severe TBI experienced during early childhood and that injury severity correlated strongly with FA is provided. Expand
fMRI study of language lateralization in children and adults
The findings indicate that language lateralization to the dominant hemisphere increases between the ages 5 and 20 years, plateaus between 20 and 25 years, and slowly decreases between 25 and 70 years. Expand
Infant brain probability templates for MRI segmentation and normalization
The two-pass segmentation approach taken here for infant T1W brain images has provided high quality tissue probability maps for GM, WM, and CSF, in infant brain images. Expand