• Publications
  • Influence
Population based study of fatigue and psychological distress
Abstract Abstract Objectives: To determine the prevalence of fatigue in the general population and the factors associated with fatigue. Design: Postal survey. Setting: Six general practices inExpand
  • 585
  • 38
The prevalence and morbidity of chronic fatigue and chronic fatigue syndrome: a prospective primary care study.
OBJECTIVES This study examined the prevalence and public health impact of chronic fatigue and chronic fatigue syndrome in primary care patients in England. METHODS There were 2376 subjects, aged 18Expand
  • 367
  • 34
A PET study of voluntary movement in schizophrenic patients experiencing passivity phenomena (delusions of alien control).
Schizophrenic patients experiencing passivity phenomena believe their thoughts and actions to be those of external, or alien, entities. We wished to test the hypothesis that voluntary motor action inExpand
  • 420
  • 19
Patterns of cerebral blood flow in schizophrenia.
Positron emission tomography was used to study the relationship between rCBF and symptom profiles in 30 schizophrenic patients. Factor analysis confirmed that the symptoms segregated into threeExpand
  • 692
  • 18
Mismatch negativity potentials and cognitive impairment in schizophrenia
Cognitive impairment in schizophrenia is an important predictor of clinical and social outcome. In this preliminary study, the correlation between cognitive status and deficits in mismatch negativityExpand
  • 229
  • 18
Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia
OBJECTIVE A pilot study of the density of dendritic spines on pyramidal neurons in layer III of human temporal and frontal cerebral neocortex in schizophrenia. METHODS Postmortem material from aExpand
  • 616
  • 16
Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function
Schizophrenia is a severe psychiatric disorder with a world-wide prevalence of 1%. The pathophysiology of the illness is not understood, but is thought to have a strong genetic component with someExpand
  • 137
  • 11
Impairment in frontal but not temporal components of mismatch negativity in schizophrenia.
Impairment in mismatch negativity (MMN) potentials is a robust finding in schizophrenia. While previous studies suggested that MMN in man is generated by a single dipole source bilaterally in theExpand
  • 113
  • 6
Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia
The molecular basis of schizophrenia is poorly understood; however, different brain regions are believed to play distinct roles in disease symptomology. We have studied gene expression in theExpand
  • 51
  • 6