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Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation
The standardized score facilitates future research concerning bacterial vaginosis because it provides gradations of the disturbance of vaginal flora which may be associated with different levels of risk for pregnancy complications.
Tenofovir-based preexposure prophylaxis for HIV infection among African women.
None of the drug regimens evaluated reduced the rates of HIV-1 acquisition in an intention-to-treat analysis, and adherence to study drugs was low.
Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisition.
Treatment of BV and promotion of vaginal colonization with lactobacilli should be evaluated as potential interventions to reduce a woman's risk of acquiring HIV-1, gonorrhea, and trichomoniasis.
Bacterial vaginosis is a strong predictor of Neisseria gonorrhoeae and Chlamydia trachomatis infection.
- H. Wiesenfeld, S. Hillier, M. Krohn, D. Landers, R. Sweet
- Medicine, BiologyClinical Infectious Diseases
- 1 March 2003
Bacterial vaginosis was a strong predictor of gonorrhea and chlamydial infection among subjects who reported recent exposure to a male partner with urethritis, and the importance of vaginal flora in the defense against STD acquisition is supported.
The identification of vaginal Lactobacillus species and the demographic and microbiologic characteristics of women colonized by these species.
Vaginal lactobacilli isolated from 215 sexually active women were identified using whole-chromosomal DNA probes to 20 American Type Culture Collection Lactobacillus strains and were positively associated with being white, age >/=20 years, barrier contraceptive usage, and lower frequency of bacterial vaginosis and gonorrhea.
Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women.
A monthly vaginal ring containing dapivirine reduced the risk of HIV-1 infection among African women, with increased efficacy in subgroups with evidence of increased adherence.
Association between Bacterial Vaginosis and Preterm Delivery of a Low-Birth-Weight Infant
The women with bacterial vaginosis were more likely to be unmarried, to be black, to have low incomes, and to have previously delivered low-birth-weight infants.
A review of premature birth and subclinical infection.
The Relationship of Amniotic Fluid Cytokines and Preterm Delivery, Amniotic Fluid Infection, Histologic Chorioamnionitis, and Chorioamnion Infection
- S. Hillier, S. Witkin, M. Krohn, D. H. Watts, N. Kiviat, D. Eschenbach
- Medicine, BiologyObstetrics and gynecology
- 1 June 1993
The hypothesis that infection is one cause of preterm delivery, operating via a mechanism involving induction of cytokine production, is supported.
The association of occult amniotic fluid infection with gestational age and neonatal outcome among women in preterm labor.
Elevated C-reactive protein levels and a positive AF Gram stain were the two most sensitive and specific methods to predict positive AF cultures that were associated with respiratory distress syndrome, bronchopulmonary dysplasia, and neonatal death.