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Increases in heart rate variability with successful treatment in patients with major depressive disorder.
Findings indicate that pharmacologic treatment leading to improvement in MDD is associated with increased HRV, and brief measures of HRV could be developed as a useful adjunctive, physiologic measure of treatment response to pharmacotherapy in clinical trials and other settings.
Modification of CAPS-1 for diagnosis of PTSD in Afghan refugees.
A DSM-III-R based instrument for the assessment of posttraumatic stress disorder (PTSD) was modified to accommodate cultural differences and translated into the Afghan languages Pushto and Farsi (Dari) and administered to 30 Afghan refugees living in the United States.
Event-related potential amplitude/intensity slopes predict response to antidepressants.
The conclusion that P2 amplitude/intensity slope may be a predictor of response to treatment with antidepressant medication with patients diagnosed with major depressive disorder is supported.
Antidepressants Augment Natural Killer Cell Activity: In vivo and in vitro
The enhancing effects of antidepressants on NKCA in vivo and in vitro indicate a possible direct drug interaction with lymphoid cells during pharmacotherapy, suggesting that pharmacologic treatment of depression may result in enhanced immune competence as indexed by enhanced NKCA and that NKCA could be pharmacologically augmented with antidepressants in individuals with compromised immune function.
Prenatal alcohol and stress interact to attenuate ejaculatory behavior, but not serum testosterone or LH in adult male rats.
It appears that the androgen threshold for ejaculatory behavior is elevated in males prenatally exposed to alcohol plus stress and cannot be realized with normal testosterone titers, but it can be attained with exogenous hormone administration.
Amplitude/intensity functions of auditory event-related potentials predict responsiveness to bupropion in major depressive disorder.
Results further support the previous finding that ERP amplitude/intensity functions measured under a stimulus intensity modulation paradigm provide information about the likelihood of a positive therapeutic response to antidepressant pharmacotherapy in patients with MDD and extends these results to bupropion, a pharmacologically atypical antidepressant agent.
Brain structure and function in sexual molesters of children and adolescents.
Variations from control values in rCBF and characteristics of CT head scans for the sex offenders suggest a role for cerebral dysfunction in the etiology of their aberrant behavior.