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Acute upper gastrointestinal bleeding in the UK: patient characteristics, diagnoses and outcomes in the 2007 UK audit

TLDR
AUGIB continues to result in substantial mortality although it appears to be lower than in 1993, and Mortality is particularly high among inpatients and those bleeding from varices or upper gastrointestinal malignancy.
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Use of endoscopy for management of acute upper gastrointestinal bleeding in the UK: results of a nationwide audit

TLDR
This audit has found continuing delays in performing endoscopy after AUGIB and underutilisation of standard endoscopic therapy particularly for variceal bleeding.
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National audit of the use of surgery and radiological embolization after failed endoscopic haemostasis for non‐variceal upper gastrointestinal bleeding

TLDR
This study examined the use, clinical characteristics and outcomes of patients receiving salvage surgery or TAE after failed endoscopic haemostasis for NVUGIB.
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Outcomes following early red blood cell transfusion in acute upper gastrointestinal bleeding

Aliment Pharmacol Ther 2010; 32: 215–224
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Acute variceal haemorrhage in the United Kingdom: patient characteristics, management and outcomes in a nationwide audit.

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The epidemiology of hyperferritinaemia.

TLDR
Alcohol related liver disease, haemat-ological disease, renal failure and neoplasia are much more common causes of marked hyperferritinaemia than haemochromatosis, and the role of weight loss in hyperferittinaemia may warrant further investigation.
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Mortality From Acute Upper Gastrointestinal Bleeding in the United Kingdom: Does It Display a “Weekend Effect”?

TLDR
In this large prospective study of acute upper gastrointestinal bleeding in the United Kingdom, there was no increase in mortality for weekend vs. weekday presentation despite patients being more critically ill and having greater delays to endoscopy at weekends.
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Poor Outcomes in Hospitalized Patients With Gastrointestinal Bleeding: Impact of Baseline Risk, Bleeding Severity, and Process of Care

TLDR
Differences in baseline characteristics explain some but not all of the greater mortality of IPs with AUGIB, which present with both higher baseline risks and more severe bleeding.
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Red cell transfusion for the management of upper gastrointestinal haemorrhage.

TLDR
The studies in this review do not provide useful data regarding outcomes following red blood cell transfusion for acute upper gastrointestinal haemorrhage and appear to exclude large survival benefit.
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The role of blood transfusion in the management of upper and lower intestinal tract bleeding.

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