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Reassortment and Insertion-Deletion Are Strategies for the Evolution of Influenza B Viruses in Nature
ABSTRACT The evolution of influenza B viruses is poorly understood. Reassortment of influenza B viruses in nature as a means of genetic variation has not been considered to be a major contributor to… Expand
Differential Narrow Focusing of Immunodominant Human Immunodeficiency Virus Gag-Specific Cytotoxic T-Lymphocyte Responses in Infected African and Caucasoid Adults and Children
ABSTRACT Cytotoxic T-lymphocyte (CTL) activity plays a central role in control of viral replication and in determining outcome in cases of human immunodeficiency virus type 1 (HIV-1) infection.… Expand
Severe hand, foot and mouth disease associated with Coxsackievirus A10 infections in Xiamen, China in 2015.
- Mengyuan Chen, S. He, +6 authors N. Xia
- Journal of clinical virology : the official…
- 1 August 2017
BACKGROUND Coxsackievirus A10 (CV-A10) is one of the etiological agents associated with hand, foot and mouth disease (HFMD) and usually causes mild cases. During 2009-2014, no severe cases caused by… Expand
Expression and immunoactivity of chimeric particulate antigens of receptor binding site-core antigen of hepatitis B virus.
- Hai-Jie Yang, M. Chen, +7 authors N. Xia
- Medicine, Biology
- World journal of gastroenterology
- 28 January 2005
AIM To improve the immunogenicity of receptor binding site of hepatitis B virus (HBV) on preS1 antigen using HBV core antigen as an immuno-carrier. METHODS One to 6 tandem copies of HBV preS1… Expand
[HEV capsid protein interacts with CYP 2A6 and decreases its coumarin 7-hydroxylation activity].
E2 is a recombinant hepatitis E virus capsid protein including its main antigenic determinants but lacking of the particle assembling domain. P239 was the C-terminal extending protein of E2 and could… Expand
Studies on the interaction between HSP90 and hepatitis E virus recombinant particle P239
Objective To identify the protein interacting with hepatitis E virus(HEV) recombi-nant capsomeric particles(P239). Methods Protein interacting with HEV was analyzed by the pull-down, MALDI-TOF-MS,… Expand
[The etiological identification of an aseptic encephalitis outbreak (ten cases) in a hospital of Xiamen city, 2011].
- S. He, Xuerong Xu, +5 authors Jian-jun Niu
- Zhonghua yu fang yi xue za zhi [Chinese journal…
- 1 July 2011
OBJECTIVE To identify the etiology of an aseptic encephalitis outbreak (ten cases) in a hospital of Xiamen city from 11 to 17 May, 2011. METHODS A total of ten patients' throat swabs, anal swabs… Expand
[Recombinant HEV caspid protein p239 specifically attached on HepG2 cells and blocked the infection of wild-type HEV on liver cells].
- Ji Miao, Zi-Zheng Zheng, +6 authors N. Xia
- Chemistry, Medicine
- Bing du xue bao = Chinese journal of virology
- 1 July 2007
By using Western blot and immunofluorescence assays, the recombinant HEV capsid protein p239 was found specifically attached to the HepG2 cell surface and entered to the cytoplasm with the increase… Expand
The Establishment of Cellular Attachment Model for Hepatitis E Virus(HEV) and Its Application in the Identification of HEV Cellular Attachment Region
We have previously expressed a recombinant hepatitis E virus capsid protein p239(ORF2,aa368-606) which showed good immunogenicity and reactivity,and has been confirmed to have a simulated structure… Expand