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Chrysin suppresses LPS-stimulated proinflammatory responses by blocking NF-κB and JNK activations in microglia cells
Apigenin inhibits the production of NO and PGE2 in microglia and inhibits neuronal cell death in a middle cerebral artery occlusion-induced focal ischemia mice model
6-Shogaol, a ginger product, modulates neuroinflammation: A new approach to neuroprotection
Inhibitory effects of arbutin on melanin biosynthesis of α-melanocyte stimulating hormone-induced hyperpigmentation in cultured brownish guinea pig skin tissues
It is found that arbutin both inhibits melanin production in B16 cells induced with α-MSH and decreases tyrosinase activity in a cell-free system, and the hyperpigmentation effects of α- MSH were abrogated by the addition of arbutIn to brownish guinea pig and human skin tissues, suggesting that ar butin may be a useful agent for skin whitening.
Acacetin protects dopaminergic cells against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neuroinflammation in vitro and in vivo.
It is suggested that acacetin can protect DA neurons against the neurotoxicity involved in PD via its anti-inflammatory action.
Acacetin Attenuates Neuroinflammation via Regulation the Response to LPS Stimuli In Vitro and In Vivo
The results suggest that acacetin may act as a potential therapeutic agent for brain diseases involving neuroinflammation and ischemia, and significantly suppressed microglial activation.
Biphenyls from Berberis koreana.
Three new biphenyls were isolated from the n-hexane-soluble fraction of the MeOH extract of the trunk of Berberis koreana and exhibited cytotoxic activity against the SK-MEL-2 skin melanoma cell line and inhibited NO production in LPS-activated BV-2 cells, a microglial cell line.
Narirutin fraction from citrus peels attenuates LPS‐stimulated inflammatory response through inhibition of NF‐κB and MAPKs activation
A microfluidic device for evaluating the dynamics of the metabolism-dependent antioxidant activity of nutrients.
This microfluidic system can serve as a novel in vitro platform for predicting the antioxidant activity of various food components in a more physiologically realistic manner, as well as for studying the mechanism of action of such food components.
Bioactive phenolic constituents from the seeds of Pharbitis nil.
- Ki Hyun Kim, S. Ha, Sang-Un Choi, S. Kim, K. Lee
- Chemistry, MedicineChemical & pharmaceutical bulletin
- 1 November 2011
Two new lignans and a new phenylethanoid glycoside, termed pharbiniloside, and 22 known compounds, were isolated from the ethanol extract of the seeds of Pharbitis nil, determining the structures of the new compounds on the basis of spectroscopic analyses.