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Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system.
Rho GTPases play a fundamental role in a variety of biological processes ranging from the reorganization of the actin cytoskeleton to the regulation of cell proliferation. The activation of RhoExpand
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Percutaneous pedicle screw fixation of the lumbar spine: preliminary clinical results.
OBJECT Standard techniques for pedicle screw fixation of the lumbar spine involve open exposures and extensive muscle dissection. The purpose of this study was to report the initial clinicalExpand
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Lineage-Specific Modulation of Interleukin 4 Signaling by Interferon Regulatory Factor 4
Interleukin (IL)-4 is an immunoregulatory cytokine that exerts distinct biological activities on different cell types. Our studies indicate that interferon regulatory factor (IRF)-4 is both a targetExpand
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The P.F.C. sigma RP-F TKA designed for improved performance: a matched-pair study.
The press fit condylar P.F.C. Sigma RP-F (rotating-platform, high flexion) knee is designed to provide a range of motion (ROM) of 155 degrees without compromising wear, polyethylene contact stresses,Expand
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T Cell Receptor Engagement Leads to the Recruitment of IBP, a Novel Guanine Nucleotide Exchange Factor, to the Immunological Synapse*
Reorganization of the actin cytoskeleton is crucial to the formation and function of the immunological synapse. Rho GTPases are critical mediators of cytoskeletal reorganization, and their activityExpand
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Biodegradation of tetrachloroethylene in upflow anaerobic sludge blanket reactor
Abstract The laboratory study using upflow anaerobic sludge blanket (UASB) reactor in high strength wastewater containing tetrachloroethylene (PCE) was carried out to develop granular sludge in theExpand
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The role of the open abdomen procedure in managing severe abdominal sepsis: WSES position paper
The open abdomen (OA) procedure is a significant surgical advance, as part of damage control techniques in severe abdominal trauma. Its application can be adapted to the advantage of patients withExpand
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Left-sided Amyand's hernia.
The chance finding of the vermiform appendix lying within an inguinal hernia occurs in approximately one percent of cases of inguinal hernia, and is known as an Amyand's hernia. We report a rareExpand
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Osteolysis after total knee arthroplasty.
Osteolysis ranks as the most significant cause of revision surgery in both total hip arthroplasty and total knee arthroplasty (TKA). The factors leading to osteolysis in TKA are unique and sometimesExpand
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Comparison of a Fistulectomy and a Fistulotomy with Marsupialization in the Management of a Simple Anal Fistula: A Randomized, Controlled Pilot Trial
Purpose This randomized clinical trial was conducted to compare a fistulectomy and a fistulotomy with marsupialization in the management of a simple anal fistula. Methods Forty patients with simpleExpand
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