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- Publications
- Influence
PIK3CA mutations are associated with lower rates of pathologic complete response to anti-human epidermal growth factor receptor 2 (her2) therapy in primary HER2-overexpressing breast cancer.
- S. Loibl, G. von Minckwitz, +22 authors C. Denkert
- Medicine
- Journal of clinical oncology : official journal…
- 10 October 2014
PURPOSE
Phosphatidylinositol 3-kinase (PI3K)/AKT pathway aberrations are common in breast cancer, with mutations in PIK3CA being the most common. This study investigated the association between… Expand
Preparation of transgenic Dunaliella salina for immunization against white spot syndrome virus in crayfish
- Shuying Feng, Wenpo Feng, +5 authors N. Zhang
- Biology, Medicine
- Archives of Virology
- 1 March 2014
Although a white spot syndrome virus (WSSV) subunit vaccine could significantly enhance the immune response and benefit the shrimp host, its practical application is currently not feasible because of… Expand
Abstract S4-06: PIK3CA mutation predicts resistance to anti-HER2/chemotherapy in primary HER2-positive/hormone-receptor-positive breast cancer – Prospective analysis of 737 participants of the…
- S. Loibl, C. Denkert, +20 authors G. Minckwitz
- Medicine
- 15 December 2013
Background: Phosphatidylinositol 3-kinase (PI3K)/AKT pathway aberrations are common in breast cancer (BC), PIK3CA mutations being the most common. Mutations are frequently found in hot-spots located… Expand
PIK3CA H1047R Mutation Associated with a Lower Pathological Complete Response Rate in Triple-Negative Breast Cancer Patients Treated with Anthracycline-Taxane–Based Neoadjuvant Chemotherapy
- S. Guo, S. Loibl, G. von Minckwitz, S. Darb-Esfahani, B. Lederer, C. Denkert
- Medicine
- Cancer research and treatment : official journal…
- 4 February 2020
Purpose PIK3CA, encoding for subunit p110a of phosphatidylinositol 3 kinase, is frequently mutated in breast cancer. PIK3CA mutation was predictive for pathological complete response (pCR) in human… Expand
The Additive Operator Preserving Birkhoff Orthogonal
- S. Guo
- Mathematics
- 8 March 2019
The Birkhoff orthogonal plays an important role in the geometric study of Banach spaces. It has been con rmed that a Birkhoff orthogonality preserving linear operator between two normed linear spaces… Expand
The taxane-based chemotherapy triplet is superior to the doublet in one to nine node-positive but not node-negative triple-negative breast cancer: results from a retrospective analysis
- S. Guo, Yong-gang Shi, +4 authors X. Li
- Medicine
- Journal of Cancer
- 23 September 2020
Background: Taxane-based regimens that are frequently used in adjuvant chemotherapy in early triple-negative breast cancer (TNBC) include a three-drug regimen (TAC and AC-T) and a two-drug regimen… Expand