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Impaired Executive Function in Contemplated and Attempted Suicide in Late Life.
OBJECTIVE: Executive deficits may play an important role in late-life suicide. Yet, current evidence in this area is inconclusive and does not indicate whether these deficits are broadly associatedExpand
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Course of cognitive impairment following attempted suicide in older adults
Cognitive impairment has been associated with late‐life suicidal behavior. Without longitudinal data it is unclear whether these are transient features of a depressive state or stable impairments. WeExpand
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  • 1
Exercise effects on depression: Possible neural mechanisms.
Depression is a syndrome of stress- and emotion-dysregulation, involving compromised structural integrity of frontal-limbic networks. Meta-analytic evidence indicates that volumetric reductions inExpand
  • 42
The BDNF Val66Met polymorphism does not moderate the effect of self-reported physical activity on depressive symptoms in midlife
The brain-derived neurotrophic factor (BDNF) Val66Met single nucleotide polymorphism may be associated with clinical and subsyndromal depression, but physical activity improves mood and increasesExpand
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  • Open Access
Role of Brain Structure in Predicting Adherence to a Physical Activity Regimen
Objective Physical activity (PA) is important for maintaining health throughout the lifespan. However, adherence to PA regimens is poor with approximately 50% of older adults terminating activityExpand
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Exercise for Depression: A Feasibility Trial Exploring Neural Mechanisms.
OBJECTIVE The aim of this study was to test the feasibility of an exercise augmentation to pharmacotherapy in depressed younger and older adults while exploring neural mechanisms. METHODS AExpand
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A Systematic Review of Evidence for a Role of Rest-Activity Rhythms in Dementia
Background: Rest-activity rhythm (RAR) disruption may be a risk factor for dementia that can be objectively measured with wearable accelerometers. It is possible that risk monitoring and preventiveExpand
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  • Open Access
Exercise as a Way of Capitalizing on Neuroplasticity in Late Adulthood
The increasing proportion of older adults in the population is expected to lead to an increased prevalence of age-related diseases, including cognitive decline and impairment. It is imperative toExpand
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  • Open Access
Is There a Dose-Response Relationship Between Exercise and Cognitive Function in Older Adults?