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Magnesium transport in Salmonella typhimurium. Regulation of mgtA and mgtB expression.
TLDR
It is reported that 63Ni2+ is transported into the cell by all three of the S typhimurium Mg2+ transport systems, and at least two distinct mechanisms are responsible for regulation of the mgtA and mgtB transcription in response to extracellular cation concentration. Expand
Thioltransferase is a specific glutathionyl mixed disulfide oxidoreductase.
TLDR
Thioltransferase (glutaredoxin) appears to be specific for glutathione-containing mixed disulfides, and in separate experiments, TTase from rat liver displayed analogous selectivity. Expand
Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).
TLDR
Observations indicate that A beta s ending at A beta 42(43), which are a minor component of the A beta in human cerebrospinal fluid and plasma, are critically important in AD where they deposit selectively in plaques of all kinds. Expand
Thioltransferase in human red blood cells: purification and properties.
TLDR
A physiological role for the thioltransferase in erythrocyte sulfhydryl homeostasis is suggested and the enzyme purified to apparent homogeneity from human red blood cells is suggested. Expand
Thioltransferase in human red blood cells: kinetics and equilibrium.
TLDR
Two substrate kinetic studies of HRBC TTase and rat liver TTase gave patterns of intersecting lines on double-reciprocal plots, indicating a sequential mechanism for the TTase reactions, rather than a ping-pong mechanism. Expand
Amyloid β Protein (Aβ) in Alzheimeri's Disease Brain
Biochemical and immunocytochemical analyses were performed to evaluate the composition of the amyloid β protein (Aβ) deposited in the brains of patients with Alzheimer's disease (AD). To quantitateExpand
The glucose transporter of the human brain and blood‐brain barrier
TLDR
The identified and characterized the glucose transporter in the human cerebral cortex, cerebral microvessels, and choroid plexus by specific D‐glucose‐displaceable [3H]cytochalasin B binding, and concludes that human brain microvessel are richly endowed with a glucose transport moiety similar in molecular weight and antigenic characteristics to that of human erythrocytes and brainmicrovessels of other mammalian species. Expand
The primary structure and properties of thioltransferase (glutaredoxin) from human red blood cells
TLDR
Although this human red blood Cell glutaredoxin (hRBC Grx) is highly homologous to the 3 other mammalian Grx proteins whose sequences are known, there are a number of significant differences. Expand
Glucose Transporter of the Blood‐Brain Barrier and Brain in Chronic Hyperglycemia
TLDR
Findings do not support the hypothesis that glucose transporters in brain microvessels comprising the blood‐brain barrier are “down‐regulated” in chronic hyperglycemia and have no effect on the density or affinity of specific binding of cytochalasin B to cerebral cortical membranes. Expand
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