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Altered amygdala-prefrontal response to facial emotion in offspring of parents with bipolar disorder.
This study aimed to identify neuroimaging measures associated with risk for, or protection against, bipolar disorder by comparing youth offspring of parents with bipolar disorder versus youthExpand
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Preliminary investigation of the relationships between sleep duration, reward circuitry function, and mood dysregulation in youth offspring of parents with bipolar disorder.
BACKGROUND Altered reward circuitry function is observed in individuals with bipolar disorder (BD) and their unaffected offspring (OBP). While OBP are at elevated risk for BD, modifiable risk factorsExpand
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A pathway linking reward circuitry, impulsive sensation-seeking and risky decision-making in young adults: identifying neural markers for new interventions
High trait impulsive sensation seeking (ISS) is common in 18–25-year olds, and is associated with risky decision-making and deleterious outcomes. We examined relationships among: activity in rewardExpand
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Pupillary Motility: Bringing Neuroscience to the Psychiatry Clinic of the Future
  • S. Graur, G. Siegle
  • Psychology, Medicine
  • Current Neurology and Neuroscience Reports
  • 19 June 2013
Modern pupillometry has expanded the study and utility of pupil responses in many new domains, including psychiatry, particularly for understanding aspects of cognitive and emotional informationExpand
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Altered functioning of reward circuitry in youth offspring of parents with bipolar disorder.
BACKGROUND Offspring of parents with bipolar disorder (BD) (BO) are at higher risk of BD than offspring of parents with non-BD psychopathology (NBO), although both groups are at higher risk thanExpand
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Towards Personalized, Brain-Based Behavioral Intervention for Transdiagnostic Anxiety: Transient Neural Responses to Negative Images Predict Outcomes Following a Targeted Computer-Based Intervention
Objective: Clinical anxiety is prevalent, highly comorbid with other conditions, and associated with significant medical morbidity, disability, and public health burden. Excessive attentionalExpand
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Intrinsic functional connectivity correlates of person-level risk for bipolar disorder in offspring of affected parents
Offspring of parents with bipolar disorder (OBP) are at increased risk to develop bipolar disorder (BD). Alterations in resting-state functional connectivity (rsFC) have been identified in OBP;Expand
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Diffusion imaging markers of bipolar versus general psychopathology risk in youth at-risk
Bipolar disorder (BD) is highly heritable. Thus, studies in first-degree relatives of individuals with BD could lead to the discovery of objective risk markers of BD. Abnormalities in white matterExpand
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Mediation by anxiety of the relationship between amygdala activity during emotion processing and poor quality of life in young adults
Young adults often experience psychological distress and poor quality of life (QoL). Yet, there are no objective neural markers to accurately guide interventions to help improve these measures. WeExpand
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Reduced focal fiber collinearity in the cingulum bundle in adults with obsessive-compulsive disorder
Obsessive-compulsive disorder (OCD) is a disabling condition, often associated with a chronic course. Given its role in attentional control, decision-making, and emotional regulation, the anteriorExpand
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