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Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism
Autism spectrum conditions (ASCs) are heritable conditions characterized by impaired reciprocal social interactions, deficits in language acquisition, and repetitive and restricted behaviors andExpand
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Computerized video analysis of social interactions in mice
The study of social interactions in mice is used as a model for normal and pathological cognitive and emotional processes. But extracting comprehensive behavioral information from videos ofExpand
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Adult Male Mice Emit Context-Specific Ultrasonic Vocalizations That Are Modulated by Prior Isolation or Group Rearing Environment
Social interactions in mice are frequently analysed in genetically modified strains in order to get insight of disorders affecting social interactions such as autism spectrum disorders. DifferentExpand
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Working memory, response selection, and effortful processing in rats with medial prefrontal lesions.
This study examined the effects of lesions of the prelimbic area of the rat prefrontal cortex on acquisition and retention of nonmatching (NMTS) and matching-to-sample (MTS) tasks. Both tasksExpand
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Executive and social behaviors under nicotinic receptor regulation
Nicotine enhances several cognitive and psychomotor behaviors, and nicotinic antagonists cause impairments in tasks requiring cognitive effort. To explore the contribution of nicotinic receptors toExpand
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Interplay of β2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion
Acetylcholine (ACh) is a known modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic ACh receptors (nAChRs). Yet, the subunit composition and specificExpand
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Prefrontal nicotinic receptors control novel social interaction between mice
Social behavior is a defining mammalian feature that integrates emotional and motivational processes with external rewarding stimuli. It is thus an appropriate readout for complex behaviors, yet itsExpand
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Monoamine Oxidase Inhibitors Allow Locomotor and Rewarding Responses to Nicotine
Although nicotine is generally considered to be the main compound responsible for the addictive properties of tobacco, experimental data indicate that nicotine does not exhibit all theExpand
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Genetic dissociation of two behaviors associated with nicotine addiction: Beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome
RationaleNicotine addiction is characterized by two distinct behaviors, chronic compulsive self-administration and the induction of a withdrawal syndrome upon cessation of nicotineExpand
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Medial prefrontal lesions in the rat and spatial navigation: evidence for impaired planning.
Rats with medial prefrontal cortical lesions were tested in a modified water maze navigation task. In Stage 1, the rats were trained to locate a hidden platform from a single start location. TheyExpand
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