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ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: executive summary.
The 2017-18 FACC/FACP/FCP/FCGC curriculum vitae were presented at a special session at the annual meeting of the American College of Cardiology in Los Angeles, California. Expand
Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in-Congestive Heart Failure (MERIT-HF)
Metoprolol controlled release/extended release (CR/XL) once daily in addition to standard therapy improved survival and the drug was well tolerated. Expand
Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart
In this study of patients with symptomatic heartfailure, metoprolol CR/XL improved survival, reduced the need for hospitalizations due to worsening heart failure, improved NYHA functional class, and had beneficial effects on patient well-being. Expand
Exercise Training in Patients with Heart Failure A Randomized, Controlled Trial
The role of exercise training in the treatment of heart failure remains a paradox, because exercise intolerance is a characteristic finding in patients with this condition and the mechanisms by which this improvement occurs are uncertain. Expand
A canine model of chronic heart failure produced by multiple sequential coronary microembolizations.
It is concluded that multiple intracoronary embolizations with microspheres, separated in time, can lead to chronic heart failure in dogs and manifests many of the sequelae of heart failure that result from loss of contractile myocardium. Expand
Predictors of total mortality and sudden death in mild to moderate heart failure. Captopril-Digoxin Study Group.
The relation between baseline clinical variables and subsequent mortality was examined in 295 patients with mild to moderate heart failure who participated in a multicenter trial comparing the effectExpand
Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure.
It is concluded that morphological and biochemical features of cardiocyte apoptosis exist in the left ventricular myocardium of dogs with chronic heart failure. Expand
A randomized controlled trial evaluating the safety and efficacy of cardiac contractility modulation in advanced heart failure.
In the overall target population, CCM did not improve VAT (the primary end point) but did improve pVo₂ and MLWHFQ and post hoc, hypothesis-generating analysis identified a subgroup in which all parameters were improved by CCM. Expand
Delay in hospitalization during the acute coronary period.
The decision time was longer in those patients who arrived by car rather than by ambulance, increased progressively with age and was twice as long for women as for men, and it was generally longer when the symptom occurred during daylight hours than when it occurred at night. Expand