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Basis for changes in DNA recognition by the EcoR124 and EcoR124/3 type I DNA restriction and modification enzymes.
EcoR124 and EcoR124/3 are type I DNA restriction and modification systems. The EcoR124/3 system arose from the EcoR124 system some 15 years ago and at the electron microscopic DNA heteroduplex levelExpand
Cloning, production and characterisation of wild type and mutant forms of the R.EcoK endonucleases.
The hsdR, hsdM and hsdS genes coding for R.EcoK restriction endonuclease, both with and without a temperature sensitive mutation (ts-1) in the hsdS gene, were cloned in pBR322 plasmid and introducedExpand
Host specificity of DNA in Haemophilus influenzae: the restriction and modification systems in strains Rb and Rf.
Summary: Haemophilus influenzae Rf possesses two distinct host specificity systems F1 and F2 each of which is able to restrict and modify Haemophilus phage HP1c1, while strain Rb possesses only oneExpand
Restriction and modification of bacteriophages by R+ strains of Escherichia coli K12.
Complementation analysis of temperature-sensitive host specificity mutations in Escherichia coli.
Abstract A selection procedure was devised for the isolation of temperature-sensitive mutants of Escherichia coli Kl2 unable to restrict foreign DNA. Many of the non-restricting mutants isolated alsoExpand
Genetics of host-controlled restriction and modification in Escherichia coli.
The sites of mutations affecting host-controlled modification (HCM) have been mapped in E. coli K and E. coli B by conjugation and transduction experiments between mutants. These mutations all mapExpand