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Quercetin Stimulates Insulin Secretion and Reduces the Viability of Rat INS-1 Beta-Cells
It is concluded that quercetin acutely stimulates insulin release, presumably by transient KATP channel inhibition and ICa stimulation, most likely by inhibition of PI3K/Akt signaling. Expand
Traditional Mongolian Medicine: history and status quo
Traditional Mongolian Medicine (TMM) plays an important role within the medical system of Mongolia nowadays. This medical system is rather unknown in the Western world, and detailed information canExpand
Sesquiterpenes and Flavonoid Aglycones from a Hungarian Taxon of the Achillea millefolium Group
The investigation of a dichloromethane extract of flower heads of a Hungarian taxon of the Achillea millefolium group led to the isolation of three flavonoid aglycones, one triterpene, one germacranolide and five guaianolides, which are reported here for the first time. Expand
Secondary metabolites of Centaurea calolepis and evaluation of cnicin for anti-inflammatory, antioxidant, and cytotoxic activities
Evaluation of biological activity of cnicin establishes the potential of this compound as an anti-inflammatory and cytotoxic agent and first detailed report of secondary metabolites of C. calolepis. Expand
Walnut leaf extract inhibits PTP1B and enhances glucose-uptake in vitro.
The finding that Juglans regia leaf extract enhances glucose uptake and inhibits PTP1B provides an in vitro-based rationale for the traditional use of walnut leaf preparations against elevated blood-glucose levels. Expand
Yarrow (Achillea millefolium L. s.l.): pharmaceutical quality of commercial samples.
The main pharmacologically active principles were shown to be the essential oil (antimicrobial), proazulenes and other sesquiterpene lactones, dicaffeoylquinic acids (choleretic) and flavonoids (antispasmodic), and the quality of the drug material was very heterogenous. Expand
Chemotaxonomic relevance of sesquiterpenes within the Achillea millefolium group
The chemotaxonomic relevance of sesquiterpenoids within the Achillea millefolium group has been evaluated by means of morphological, anatomical, cytological and phytochemical data and characteristic for each species are shown. Expand
Topical anti-inflammatory activity of a new germacrane derivative from Achillea pannonica.
The topical anti-inflammatory activity of a germacrane derivative isolated from Achillea pannonica Scheele was investigated employing the Croton oil-induced dermatitis in the mouse ear and its effects on the oedematous response and on leukocytes infiltration are described. Expand
Extracts from the Mongolian traditional medicinal plants Dianthus versicolorFisch. and Lilium pumilum Delile stimulate bile flow in an isolated perfused rat liver model.
The results show that choleresis under extract application is due to a stimulation of the bile-salt-independent bile flow which might be caused by the osmotic power of the extracts (hydrocholeresis). Expand
Extracts from Leonurus sibiricus L. increase insulin secretion and proliferation of rat INS-1E insulinoma cells.
The finding that extracts from Leonurus sibiricus L. enhance insulin secretion and/or foster cell proliferation may provide possible explanations for the underlying therapeutic principles in the empirical use of LS-containing formulations in DM and DM-related disorders as applied in TMM. Expand