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Antimicrobial therapy in veterinary medicine
- S. Giguère
- Biology, Medicine
Clinical manifestations, diagnosis, treatment, and prevention of Rhodococcus equi infections in foals.
Cytokine induction in pulmonary airways of horses with heaves and effect of therapy with inhaled fluticasone propionate.
Role of the 85-Kilobase Plasmid and Plasmid-Encoded Virulence-Associated Protein A in Intracellular Survival and Virulence of Rhodococcus equi
- S. Giguère, M. Hondalus, J. Yager, P. Darrah, D. Mosser, J. Prescott
- BiologyInfection and Immunity
- 1 July 1999
Results show that the 85-kb plasmid of R. equi is essential for intracellular replication within macrophages and for development of disease in the native host, the foal, however, expression of VapA alone is not sufficient to restore the virulence phenotype.
Diagnosis, treatment, control, and prevention of infections caused by Rhodococcus equi in foals.
- S. Giguère, N. Cohen, J. Prescott
- Biology, MedicineJournal of veterinary internal medicine
- 1 November 2011
This consensus statement is to provide recommendations regarding the diagnosis, treatment, control, and prevention of infections caused by R. equi in foals.
Rhodococcus equi: clinical manifestations, virulence, and immunity.
- S. Giguère, N. Cohen, N. Slovis
- Medicine, BiologyJournal of veterinary internal medicine
- 1 November 2011
Current knowledge regarding mechanisms of virulence of, and immunity to, R. equi in foals is summarized and recommendations for the diagnosis, treatment, control, and prevention of infections caused by R. Equi are provided.
A novel lipoarabinomannan from the equine pathogen Rhodococcus equi. Structure and effect on macrophage cytokine production.
Rhodococcus equi is a major cause of foal morbidity and mortality. We have investigated the presence of lipoglycan in this organism as closely related bacteria, notably Mycobacterium tuberculosis,…
In Vitro Susceptibilities of Rhodococcus equi and Other Common Equine Pathogens to Azithromycin, Clarithromycin, and 20 Other Antimicrobials
Both AZM and CLR showed good activity against beta-hemolytic streptococci and Staphylococcus spp.
Factors associated with survival of neonatal foals with bacteremia and racing performance of surviving Thoroughbreds: 423 cases (1982-2007).
M microbial resistance to antimicrobials commonly used to treat bacteremic foals did not develop during the study period, and Thoroughbred survivors had significantly fewer wins and total earnings.
Infectious Agents Detected in the Feces of Diarrheic Foals: A Retrospective Study of 233 Cases (2003–2008)
- J. Frederick, S. Giguère, L. Sanchez
- MedicineJournal of veterinary internal medicine
- 11 September 2009
In the population studied, foals with diarrhea had a good prognosis regardless of which infectious agent was identified in the feces, and the type of infectious agent identified inthe feces or bacteremia was not significantly associated with survival.