S. Genuth

Publications191
h-index60
Citations60,568
Highly Influential Citations698
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Follow-up report on the diagnosis of diabetes mellitus.
TLDR
The International Expert Committee was convened to reexamine the classification and diagnostic criteria of diabetes, which were based on the 1979 publication of the National Diabetes Data Group and subsequent WHO study group and adopted several changes to the diagnostic criteria for diabetes and for lesser degrees of impaired glucose regulation (IFG/IGT). Expand
The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long‐Term Complications in Insulin‐Dependent Diabetes Mellitus
TLDR
Intensive therapy effectively delays the onset and slows the progression of diabetic retinopathy, nephropathy, and neuropathy in patients with IDDM. Expand
Effects of intensive glucose lowering in type 2 diabetes.
TLDR
The use of intensive therapy to target normal glycated hemoglobin levels for 3.5 years increased mortality and did not significantly reduce major cardiovascular events and identify a previously unrecognized harm of intensive glucose lowering in high-risk patients with type 2 diabetes. Expand
Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.
TLDR
Intensive diabetes therapy has long-term beneficial effects on the risk of cardiovascular disease in patients with type 1 diabetes, and changes between treatment groups remained significant after adjusting for these factors. Expand
A randomized trial of therapies for type 2 diabetes and coronary artery disease.
TLDR
Overall, there was no significant difference in the rates of death and major cardiovascular events between patients undergoing prompt revascularization and those undergoing medical therapy or between strategies of insulin sensitization and insulin provision. Expand
Report of the expert committee on the diagnosis and classification of diabetes mellitus.
TLDR
It was deemed essential to develop an appropriate, uniform terminology and a functional, working classification of diabetes that reflects the current knowledge about the disease. Expand
Effects of medical therapies on retinopathy progression in type 2 diabetes.
TLDR
Intensive glycemic control and intensive combination treatment of dyslipidemia, but not intensive blood-pressure control, reduced the rate of progression of diabetic retinopathy. Expand
Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial
TLDR
Intensive therapy did not reduce the risk of advanced measures of microvascular outcomes, but delayed the onset of albuminuria and some measures of eye complications and neuropathy. Expand
Long-term effects of intensive glucose lowering on cardiovascular outcomes.
TLDR
The use of intensive therapy for 3.7 years to target a glycated hemoglobin level below 6% reduced 5-year nonfatal myocardial infarctions but increased 5- year mortality, and such a strategy cannot be recommended for high-risk patients with advanced type 2 diabetes. Expand
Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus.
TLDR
Progression of carotid intima-media thickness was associated with age, and the EDIC base-line systolic blood pressure, smoking, the ratio of low-density lipoprotein to high-density cholesterol, and urinary albumin excretion rate and with the mean glycosylated hemoglobin value during the mean duration of the DCCT. Expand
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