• Publications
  • Influence
Second-generation aptamer-conjugated PSMA-targeted delivery system for prostate cancer therapy
Background: miR-15a and miR-16-1 have been identified as tumor suppressor genes in prostate cancer, but their safe and effective delivery to target cells is key to the successful use of thisExpand
  • 86
  • 2
  • Open Access
PLGA–PEG–PLGA hydrogel for ocular drug delivery of dexamethasone acetate
Aim: This study aims to investigate the suitability of thermosensitive triblock polymer poly-(dl-lactic acid-co-glycolic acid) (PLGA)–polyethylene glycol (PEG)–PLGA as a matrix material for ocularExpand
  • 78
  • 2
A thermo-sensitive PLGA-PEG-PLGA hydrogel for sustained release of docetaxel
The aim of this study was to investigate the suitability of poly-(d,l-lactic acid-co-glycolic acid) (PLGA)-polyethylene glycol (PEG)-PLGA triblock copolymer as a matrix material for aExpand
  • 53
  • 2
Reducible self-assembling cationic polypeptide-based micelles mediate co-delivery of doxorubicin and microRNA-34a for androgen-independent prostate cancer therapy.
The co-delivery of chemotherapeutic drugs and microRNAs (miR) represents a promising strategy for tumor therapy due to the synergistic effect achieved. In the present study, hydrophobic doxorubicinExpand
  • 45
  • 2
Anti-DR5 monoclonal antibody-mediated DTIC-loaded nanoparticles combining chemotherapy and immunotherapy for malignant melanoma: target formulation development and in vitro anticancer activity
Background The increased incidence of malignant melanoma in recent decades, along with its high mortality rate and pronounced resistance to therapy pose an enormous challenge. Novel therapeuticExpand
  • 36
  • 2
  • Open Access
Economic Burden of Individual Suffering from Atrial Fibrillation-Related Stroke in China.
OBJECTIVE Atrial fibrillation (AF) is an important risk factor for stroke. The primary purpose of this study was to estimate the 1-year direct and indirect costs of ischemic stroke in ChineseExpand
  • 13
  • 2
Functional exosome-mediated co-delivery of doxorubicin and hydrophobically modified microRNA 159 for triple-negative breast cancer therapy
Exosomes (Exo) hold great promise as endogenous nanocarriers that can deliver biological information between cells. However, Exo are limited in terms of their abilities to target specific recipientExpand
  • 9
  • 2
Current status of gene therapy for hepatocellular carcinoma, with a focus on gene delivery approaches.
Hepatocellular carcinoma (HCC) is a malignancy with high morbidity and mortality rates, especially in East Asia. Gene therapy is a potential approach for treating HCC. An efficient and safe geneExpand
  • 6
  • 2
The anti-fatigue effect of 20(R)-ginsenoside Rg3 in mice by intranasally administration.
20(R)-ginsenoside Rg3 (20(R)-Rg3) has shown multiple pharmacological activities and been considered as one of the most promising approaches for fatigue treatment. However, 20(R)-Rg3 has a lowExpand
  • 82
  • 1
  • Open Access
Aptamer-mediated delivery of docetaxel to prostate cancer through polymeric nanoparticles for enhancement of antitumor efficacy.
Treatment of aggressive prostate cancer remains a great challenge due to inadequate drug distribution into the cancerous lesions after administration. This study aimed to develop aptamer-anchoredExpand
  • 27
  • 1