Multiday acute sodium bicarbonate intake improves endurance capacity and reduces acidosis in men
- S. M. Mueller, S. Gehrig, S. Frese, C. Wagner, U. Boutellier, M. Toigo
- MedicineJournal of the International Society of Sports…
- 26 March 2013
The increase in Tlim was accompanied by an increase in [HCO3-], suggesting that acidosis might be a limiting factor for exercise at CP, and ingestion of one single NaH CO3 dose per day before the competition during multiday competitions or tournaments may be a valuable strategy for performance enhancement.
Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue
It is shown for the first time that the connective tissue‐specific lack of superoxide anion detoxification in the mitochondria results in reduced lifespan and premature onset of aging‐related phenotypes such as weight loss, skin atrophy, kyphosis (curvature of the spine), osteoporosis and muscle degeneration in mutant mice.
Exercise effects in Huntington disease
It is confirmed that HD patients are amenable to a specific exercise-induced therapeutic strategy indicated by an increased cardiovascular function and a stabilization of motor function, as indicated by the Unified Huntington’s Disease Rating Scale motor section score.
Long-Term Endurance Exercise in Humans Stimulates Cell Fusion of Myoblasts along with Fusogenic Endogenous Retroviral Genes In Vivo
It is proposed that during the pre-competitive season SC proliferation occurred following with increased cell fusion during the competitive season, and functional roles for ERV envelope proteins, especially Syncytin-1, contribute to cell fusion of myotubes.
Altered skeletal muscle (mitochondrial) properties in patients with mitochondrial DNA single deletion myopathy
Investigation of disease-related impairments in skeletal muscle properties in patients with mitochondrial myopathy found impaired mitochondrial quantity and quality and a shift towards a more glycolytic skeletal muscle phenotype.
High-load resistance exercise with superimposed vibration and vascular occlusion increases critical power, capillaries and lean mass in endurance-trained men
It is demonstrated that modification of resistance exercise by superimposing side-alternating whole-body vibration and sustained vascular occlusion induced further improvements in CP, capillarization and hypertrophy, all of which were not observed with resistance training alone.
Increased capillary tortuosity and pericapillary basement membrane thinning in skeletal muscle of mice undergoing running wheel training
Capillaries in skeletal muscles of mice undergoing long-term running wheel training change in structure, making them better adapted to the higher energy requirements of the tissue.
Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients
Endurance training is a safe and feasible option to enhance indices of energy metabolism in skeletal muscle of HD patients and may represent a potential therapeutic approach to delay the onset and/or progression of muscular dysfunction.
Myosin heavy chain expression pattern as a marker for anabolic potency: desoxymethyltestosterone (madol), norandrostendione and testosterone repress MHC-IIb expression and stimulate MHC-IId/x…
- S. Frese, M. Velders, B. Schleipen, W. Schänzer, W. Bloch, P. Diel
- BiologyArchives of Toxicology
- 1 June 2011
Results suggest that the observed MHC expression shift could serve as a molecular marker to determine anabolic activity of anabolic steroids at least in skeletal Muscle fiber type composition and myosin heavy chain expression in intact skeletal muscle of orchi rats.
Angiogenesis-related ultrastructural changes to capillaries in human skeletal muscle in response to endurance exercise.
The study suggests that intensified PC mobilization and BM thinning are related to exercise-induced angiogenesis in human skeletal muscle, whereas training per se induces EC-thickening.