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Pulmonary aspergillosis in the acquired immunodeficiency syndrome.
BACKGROUND AND METHODS Symptomatic pulmonary aspergillosis has rarely been reported in patients with the acquired immunodeficiency syndrome (AIDS). We describe the predisposing factors, the clinicalExpand
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Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome.
RECURRENT herpes simplex virus (HSV) infections are frequent in patients with the acquired immunodeficiency syndrome (AIDS). Although they are usually self-limiting in the normal host, such infecti...
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Prevalence of resistance in patients receiving ganciclovir for serious cytomegalovirus infection.
Seventy-two AIDS patients treated with ganciclovir for cytomegalovirus (CMV) disease were prospectively monitored for the development of drug-resistant virus. No resistant strains were found in 31Expand
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Oral ganciclovir for the prevention of cytomegalovirus disease in persons with AIDS. Roche Cooperative Oral Ganciclovir Study Group.
BACKGROUND In the advanced stages of the acquired immunodeficiency syndrome (AIDS), cytomegalovirus (CMV) disease, particularly vision-damaging retinitis due to CMV is common. We evaluatedExpand
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Oral ganciclovir as maintenance treatment for cytomegalovirus retinitis in patients with AIDS. Syntex Cooperative Oral Ganciclovir Study Group.
BACKGROUND Cytomegalovirus retinitis, a sight-threatening infection associated with the acquired immunodeficiency syndrome (AIDS), currently requires lifelong intravenous treatment. An effective oralExpand
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Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease.
In a human immunodeficiency virus-infected subject, cytomegalovirus (CMV) isolated 9 months after the patient began oral ganciclovir prophylaxis was resistant to ganciclovir and cidofovir andExpand
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Activation of virus replication after vaccination of HIV-1-infected individuals
Little is known about the factors that govern the level of HIV-1 replication in infected individuals. Recent studies (using potent antiviral drugs) of the kinetics of HIV-1 replication in vivo haveExpand
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Ritonavir and saquinavir combination therapy for the treatment of HIV infection.
OBJECTIVE To evaluate the safety and antiretroviral activity of ritonavir (Norvir) and saquinavir (Invirase) combination therapy in patients with HIV infection. DESIGN A multicenter, randomized,Expand
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Ulcerative and plaque-like tracheobronchitis due to infection with Aspergillus in patients with AIDS.
Tracheobronchitis is an uncommon manifestation of infection due to Aspergillus species, occurring in < 7% of cases of pulmonary aspergillosis. At least 58 cases of invasive aspergillusExpand
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Surgical outcomes in human immunodeficiency virus-infected patients in the era of highly active antiretroviral therapy.
HYPOTHESIS Matched patients who test positive or negative for human immunodeficiency virus (HIV) who are undergoing comparable operations have similar complication rates and outcomes. DESIGN AExpand
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