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Development of a high-throughput automated analyzer using biochip array technology.
BACKGROUND Use of protein array technology over conventional assay methods has advantages that include simultaneous detection of multiple analytes, reduction in sample and reagent volumes, and highExpand
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A novel multiplex-protein array for serum diagnostics of colon cancer: a case–control study
BackgroundMore than 1.2 million new cases of colorectal cancer are reported each year worldwide. Despite actual screening programs, about 50% of the patients are diagnosed at advanced tumor stagesExpand
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Diagnostic accuracy of heart-type fatty acid-binding protein for the early diagnosis of acute myocardial infarction.
OBJECTIVE The aim of this study was to evaluate the diagnostic efficacy of multiple tests-heart-type fatty acid-binding protein (H-FABP), cardiac troponin I (cTnI), creatine kinase-MB, andExpand
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Reduced plasma levels of P-selectin and L-selectin in a pilot study from Alzheimer disease: relationship with neuro-degeneration
Neurodegenerative processes associated with Alzheimer’s disease (AD) are accompanied by reactive astrogliosis and microglia activation and a role for chronic inflammation in the brain degeneration ofExpand
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The Use of Biochip Array Technology for Rapid Multimycotoxin Screening.
The main known groups of mycotoxins are aflatoxins, fumonisins, ochratoxins, type A trichothecenes (T-2 toxin and HT-2 toxin), type B trichothecenes (deoxynivalenol), and zearalenones. They areExpand
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The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung
Cystic fibrosis (CF) lung disease is an inherited condition with an incidence rate of approximately 1 in 2500 new born babies. CF is characterized as chronic infection of the lung which leads toExpand
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Automation of biochip array technology for quality results
We present the Evidence Biochip Array analyser which enables simultaneous measurement of multiple markers in a patient sample, without compromising the quality of results. Expand
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Investigation and verification of a bioluminescent biosensor for the quantitation of ara-CTP generation: a biomarker for cytosine arabinoside sensitivity in acute myeloid leukaemia.
A novel whole cell bacterial biosensor, which emits light in response to the active metabolite of cytosine arabinoside (ara-C, cytarabine), ara-CTP, has been investigated and verified. The biosensorExpand
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Development of an immunoaffinity column and an enzyme immunoassay for the screening of clenbuterol in meat samples and the practical application of this test in the screening of 1005 samples
Clenbuterol residue analysis of liver, kidney and muscle samples was performed using immunoaffinity chromatography for sample clean‐up and an enzyme‐linked immunosorbent assay (ELISA) as the means ofExpand
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Rapid determination of triazine contamination of fresh water supplies by immunoassay
A highly sensitive, competitive, enzyme‐linked immunosorbent assay (ELISA) was developed for the detection of five triazine herbicides in water samples. Low detection limits were achieved without theExpand
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