S. Filosto

Publications29
h-index6
Citations405
Highly Influential Citations18
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PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
Triple-negative breast cancers (TNBCs) have poor prognosis and lack targeted therapies. Here we identified increased copy number and expression of the PIM1 proto-oncogene in genomic data sets of… Expand
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Anaemia in cancer: pathophysiology and treatment.
Anaemia in cancer patients is multifactorial and may occur as a either a direct effect of the cancer, as a result of the cancer treatment itself, or due to chemical factors produced by the cancer.… Expand
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Cadmium induces an apoptotic response in sea urchin embryos
Abstract Cadmium is a heavy metal toxic for living organisms even at low concentrations. It does not have any biological role, and since it is a permanent metal ion, it is accumulated by many… Expand
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Environmentally relevant cadmium concentrations affect development and induce apoptosis of Paracentrotus lividus larvae cultured in vitro
Sea urchin embryos and larvae represent suitable model systems on where to investigate the effects of heavy metals on development and cell viability. Here, we tested the toxic effects of low (10−12… Expand
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Cadmium accumulation induces apoptosis in P. Lividus em- bryos
Cadmium is a heavy metal considered one of the most toxic pollutants both in terrestrial and aquatic ecosystems, which causes a series of toxic effects in differents organisms. We have previously… Expand
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High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers
BOS172722 (CCT289346) is a highly potent, selective, and orally bioavailable inhibitor of spindle assembly checkpoint kinase MPS1. BOS172722 treatment alone induces significant sensitization to… Expand
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Immunocytochemical determination of estrogen and progesterone receptors on 219 fine-needle aspirates of breast cancer. A prospective study.
Fine needle aspirates from breast carcinomas of 219 patients were examined cytologically and for the determination of estrogen receptors (ER) and, in 145 of these cases, of progesterone receptors… Expand
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PIM 1 kinase regulates cell death , tumor growth and chemotherapy response in triple-negative breast cancer
Triple-negative breast cancers (TNBCs) have poor prognosis and lack targeted therapies. Here we identified increased copy number and expression of the PIM1 proto-oncogene in genomic data sets of… Expand
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Cadmium accumulation induces apoptosis in P. lividus larvae.
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Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
Constanze Schneider, Thomas Oellerich, Hanna-Mari Baldauf, Sarah-Marie Schwarz, Dominique Thomas, Robert Flick, Hanibal Bohnenberger, Lars Kaderali, Lena Stegmann, Anjali Cremer, Margarethe Martin,… Expand
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