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The Global Deterioration Scale for assessment of primary degenerative dementia.
- B. Reisberg, S. Ferris, M. D. de Leon, T. Crook
- The American journal of psychiatry
- 30 August 1982
Cognitive decline associated with old age and consistent with the diagnosis of primary degenerative dementia is a unique clinical syndrome with characteristic phenomena and progression. The authors… Expand
An Inventory to Assess Activities of Daily Living for Clinical Trials in Alzheimer's Disease
We developed a set of informant-based items describing performance of activities of daily living (ADL) by patients with Alzheimer's disease (AD) to identify which ADL are useful for assessment of… Expand
Vitamin E and donepezil for the treatment of mild cognitive impairment.
BACKGROUND Mild cognitive impairment is a transitional state between the cognitive changes of normal aging and early Alzheimer's disease. METHODS In a double-blind study, we evaluated subjects with… Expand
Global Deterioration Scale (GDS).
Behavioral symptoms in Alzheimer's disease: phenomenology and treatment.
- B. Reisberg, J. Borenstein, S. Salob, S. Ferris, E. Franssen, A. Georgotas
- Psychology, Medicine
- The Journal of clinical psychiatry
- 1 May 1987
Limited information is available regarding the incidence, nature, and treatment of behavioral problems in Alzheimer's disease (AD). A chart review of 57 outpatients with a diagnosis of AD was… Expand
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
- S. Salloway, R. Sperling, +21 authors H. Brashear
- The New England journal of medicine
- 23 January 2014
BACKGROUND Bapineuzumab, a humanized anti-amyloid-beta monoclonal antibody, is in clinical development for the treatment of Alzheimer's disease. METHODS We conducted two double-blind, randomized,… Expand
Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials.
BACKGROUND Mild cognitive impairment (MCI) represents a transitional state between the cognitive changes of normal aging and very early dementia and is becoming increasingly recognized as a risk… Expand
Age‐associated memory impairment: Proposed diagnostic criteria and measures of clinical change — report of a national institute of mental health work group
Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. The Alzheimer's Disease Cooperative Study.
This article reports the development and psychometric properties of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change (ADCS-CGIC). At present, a number of unvalidated… Expand
Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics…
OBJECTIVE A consensus conference on the diagnosis and treatment of Alzheimer disease (AD) and related disorders was organized by the American Association for Geriatric Psychiatry, the Alzheimer's… Expand