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Synthesis, Characterization, and in vitro Antibacterial Evaluation of Barbituric Acid Derivatives
A series of 5,5′-(arylmethylene)bis[1,3-dimethyl-6-(methylamino)pyrimidine-2,4(1H,3H)-diones] have been synthesized by 2: 1 condensation of 1,3 -dimethylbarbituric acid with armatic aldehydes in the presence of methylamine and shown antibacterial activity exceeding that of ampicillin used as reference drug.
An Easy Synthetic Access to Spiro Derivatives Containing Pyrido[1,2‐a]pyrimidine and Quinoline Scaffolds and Their Antimicrobial Activity.
A series of novel spiro derivatives containing pyrido[1,2-a]pyrimidine and quinoline moieties was designed and synthesized, and their structures were characterized by 1H, 13C NMR, IR, Mass Spectral
Construction of Oxygen‐ and Nitrogen‐based Heterocycles from p‐Quinone Methides
The main focus of this review article is to cover the recent advancements in the transition‐metal, Lewis acid and base‐catalyzed/mediated synthetic transformations of the stable p‐quinone methides (p‐QMs) to oxygen‐ and nitrogen‐containing heterocycles.
Synthesis, characterization, and antimicrobial evaluation of novel spiropiperidones
Abstract Novel spiro derivatives of piperidone 4a–f were synthesized, characterized, and screened against a panel of different bacterial and fungal strains. The study revealed the potential of these