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Endovascular therapy after intravenous t-PA versus t-PA alone for stroke.
BACKGROUND Endovascular therapy is increasingly used after the administration of intravenous tissue plasminogen activator (t-PA) for patients with moderate-to-severe acute ischemic stroke, butExpand
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown. We conducted a multiancestry genome-wide-association meta-analysis in 521,612 individuals (67,162 cases andExpand
Epidemiology of Aphasia Attributable to First Ischemic Stroke: Incidence, Severity, Fluency, Etiology, and Thrombolysis
Background and Purpose— In a geographically defined population, we assessed incidence and determinants of aphasia attributable to first-ever ischemic stroke (FEIS). Methods A 1-year prospective,Expand
New ischaemic brain lesions on MRI after stenting or endarterectomy for symptomatic carotid stenosis: a substudy of the International Carotid Stenting Study (ICSS)
BACKGROUND The International Carotid Stenting Study (ICSS) of stenting and endarterectomy for symptomatic carotid stenosis found a higher incidence of stroke within 30 days of stenting compared withExpand
Quantitative assessment of diffusion abnormalities in posterior reversible encephalopathy syndrome.
BACKGROUND AND PURPOSE Previous studies have shown that lesions in posterior reversible encephalopathy syndrome are often isointense on diffusion-weighted MR images. We hypothesized that 1) apparentExpand
Long-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial
Summary Background Stenting is an alternative to endarterectomy for treatment of carotid artery stenosis, but long-term efficacy is uncertain. We report long-term data from the randomisedExpand
Volume depletion and natriuresis in patients with a ruptured intracranial aneurysm
recently it has become clear that hypona-traemia in the cerebral salt wasting syndrome is accompanied by hypovolaemia.' 2 We report a patient with cerebral salt wasting after aneurysmal subarachnoidExpand
Safety of Thrombolysis in Stroke Mimics: Results From a Multicenter Cohort Study
Background and Purpose— Intravenous thrombolysis for acute ischemic stroke is beneficial within 4.5 hours of symptom onset, but the effect rapidly decreases over time, necessitating quick diagnosticExpand
Assessment of vasogenic edema in eclampsia using diffusion imaging
Abstract We qualitatively assessed the regional distribution of vasogenic edema in a case of postpartum eclampsia. Although diffusion-weighted imaging showed no abnormalities, bilateral high signalExpand
The effect of aging on the apparent diffusion coefficient of normal-appearing white matter.
OBJECTIVE The purpose of our study was to test the hypothesis that the apparent diffusion coefficient (ADC) of normal-appearing white matter increases with advancing age. SUBJECTS AND METHODS WeExpand