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White matter structure in autism: preliminary evidence from diffusion tensor imaging
BACKGROUND Individuals with autism have severe difficulties in social communication and relationships. Prior studies have suggested that abnormal connections between brain regions important forExpand
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A Surface-Based Approach to Quantify Local Cortical Gyrification
The high complexity of cortical convolutions in humans is very challenging both for engineers to measure and compare it, and for biologists and physicians to understand it. Expand
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Attenuation of frontal asymmetry in pediatric posttraumatic stress disorder
BACKGROUND Volumetric imaging research has shown abnormal brain morphology in adults with posttraumatic stress disorder (PTSD) when compared with matched control subjects. In this article, we presentExpand
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COMT genotype predicts longitudinal cognitive decline and psychosis in 22q11.2 deletion syndrome
Although schizophrenia is strongly hereditary, there are limited data regarding biological risk factors and pathophysiological processes. In this longitudinal study of adolescents with 22q11.2Expand
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Neuroanatomy of Down's syndrome: a high-resolution MRI study.
OBJECTIVE Down's syndrome, the most common genetic cause of mental retardation, results in characteristic physical and neuropsychological findings, including mental retardation and deficits inExpand
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Decreased Anterior Cingulate Volume in Combat-Related PTSD
BACKGROUND Neuroanatomical data point to functional relationships between the anterior cingulate cortex (ACC) and subcortical centers regulating fear, in particular, the amygdala. Functional brainExpand
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Children and adolescents with velocardiofacial syndrome: a volumetric MRI study.
OBJECTIVE Velocardiofacial syndrome is a common genetic condition often accompanied by mild cognitive impairment. Children and adolescents with velocardiofacial syndrome also are at greater risk forExpand
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Regional analysis of hippocampal activation during memory encoding and retrieval: fMRI study
Investigators have recently begun to examine the differential role of subregions of the hippocampus in episodic memory. Two distinct models have gained prominence in the field. One model, outlined byExpand
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Preliminary evidence of widespread morphological variations of the brain in dyslexia
The MR images of 16 men with dyslexia and 14 control subjects were compared using a voxel-based analysis. Evidence of decreases in gray matter in dyslexic subjects, most notably in the left temporalExpand
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Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome.
OBJECTIVE Chromosome 22q11.2 deletion syndrome is a neurogenetic disorder associated with high rates of schizophrenia and other psychiatric conditions. The authors report what is to their knowledgeExpand
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