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Etiology and Pathogenesis of Osteochondrosis
The purpose of this review is to provide an overview of the disease, focusing on the most commonly cited theories, recent research findings, and the own views regarding the etiology and pathogenesis of osteochondrosis, in order to provide a better understanding of this apparently complex disease.
The pathophysiology of osteochondrosis.
An Update on the Pathogenesis of Osteochondrosis
In pigs and horses, research is currently aimed at discovering the cause of the vascular failure in osteochondrosis, and studies of spontaneous lesions suggest that failure is associated with the process of incorporating blood vessels into the advancing ossification front during growth.
Early lesions of osteochondrosis in the distal tibia of foals
Early lesions purported to play a role in the initial stages of articular OC in the distal tibia of horses were characterized by chondrocyte necrosis and likely occurred secondary to a failure of cartilage canal vascular supply to epiphyseal growth cartilage.
The effect of parentage on the prevalence, severity and location of lesions of osteochondrosis in swine.
There were significant effects of both sire and dam on the OCM scores of the offspring in most locations; however, growth rate and weight at slaughter did not influence the O CM score.
Hind limb skeletal lesions in 12-month-old bulls of beef breeds.
It is suggested that the high incidence of hind limb osteoarthritis reported in the Swedish beef bull population can be explained by the high prevalence of skeletal lesions found in the present material.