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Isolation of hypoxoside from hypoxis rooperi and synthesis of (E)-1,5-bis(3′,4′-dimethoxyphenyl)pent-4-en-1-yne
Abstract Isolation of the known diglucoside of (E) -1,5-bis(3′,4′-dihydroxyphenyl)pent-4-en-1-yne (hypoxoside) from Hypoxis rooperi is described. In vivo tests indicate low toxic properties. AExpand
A drimane sesquiterpenoid lactone from Warburgia salutaris
The stem bark of Warburgia salutaris collected in Zoutpansberg mountains yielded a new drimane sesquiterpenoid lactone, salutarisolide, along with four known drimane sesquiterpenoids warburganal,Expand
An acylated phloroglucinol with antimicrobial properties from Helichrysum caespititium.
A new acylated form of a phloroglucinol with significant antimicrobial properties was isolated by bioactivity guided fractionation from Helichrysum caespititium (Asteraceae). The structureExpand
Alkaloids from Crinum macowanii.
Analytical and pharmacological investigation of Ocotea bullata (black stinkwood) bark and leaves.
Ocotea bullata (Lauraceae), one of the top-ten traditional medicinal plants used in KwaZulu-Natal, is close to extinction through high demand and destructive harvesting methods. The stem bark isExpand
Recent findings on natural products with erectile-dysfunction activity.
Viagra has had a profound influence on the search for natural products with erectile-dysfunction activity. To date the "natural" equivalent is not in existence but several pure compounds from nature,Expand
Hypoxis hemerocallidea--not merely a cure for benign prostate hyperplasia.
The use of Hypoxis hemerocallidea Fisch. and C.A. Mey. (Hypoxidaceae) extracts for ailments other than benign prostate hyperplasia (BPH) is now a reality. The whole extract, the phytosterols, as wellExpand
Simple 1,4-benzoquinones with antibacterial activity from stems and leaves of Gunnera perpensa.
From the dichloromethane extract of the leaves and stems of Gunnera perpensa two new, simple 1,4-benzoquinones and a known benzopyran-6-ol were isolated. From the methanol extract phytol wasExpand
Antimicrobial monomeric and dimeric diterpenes from the leaves of Helichrysum tenax var tenax.
The hexane extract of fresh air-dried leaves of Helichrysum tenax (Asteraceae) afforded ent-beyer-15-en-19-ol (1), its 4-epimer ent-beyer-15-en-18-ol (2), 15beta,16beta-epoxide-ent-beyeran-19-ol (3),Expand
The African potato (Hypoxis hemerocallidea) : a chemical-historical perspective
We trace the history of the usage of lIgHypoxisl/Ig extracts from the 1960s to the present time. In particular, we follow the fortunes of the principal active component, rooperol, in detail fromExpand