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The genome sequence of Schizosaccharomyces pombe
We have sequenced and annotated the genome of fission yeast (Schizosaccharomyces pombe), which contains the smallest number of protein-coding genes yet recorded for a eukaryote: 4,824. TheExpand
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The Composite Genome of the Legume Symbiont Sinorhizobium meliloti
The scarcity of usable nitrogen frequently limits plant growth. A tight metabolic association with rhizobial bacteria allows legumes to obtain nitrogen compounds by bacterial reduction of dinitrogenExpand
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Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021
Sinorhizobium meliloti is an α-proteobacterium that forms agronomically important N2-fixing root nodules in legumes. We report here the complete sequence of the largest constituent of its genome, aExpand
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Mapping and identification of essential gene functions on the X chromosome of Drosophila
The Drosophila melanogaster genome consists of four chromosomes that contain 165 Mb of DNA, 120 Mb of which are euchromatic. The two Drosophila Genome Projects, in collaboration with Celera GenomicsExpand
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Naturally occurring melanomas in dogs as models for non‐UV pathways of human melanomas
Spontaneously occurring melanomas are frequent in dogs. They appear at the same localizations as in humans, i.e. skin, mucosal sites, nail matrix and eyes. They display variable behaviors: tumors atExpand
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NOD2/CARD15 gene polymorphisms in Crohn's disease: a genotype–phenotype analysis
Objectives Three recently identified NOD2/CARD15 mutations have been described associated with an increased susceptibility Crohn's disease (CD). Our aim was to examine the potential association ofExpand
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Ancestral T-box mutation is present in many, but not all, short-tailed dog breeds.
Dogs differ greatly in their morphological characteristics including various tail phenotypes. Congenitally short-tailed dogs are present in many breeds; however, the causative mutation located in theExpand
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A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis
Neuronal ceroid lipofuscinoses (NCLs) represent the most common group of inherited progressive encephalopathies in children. They are characterized by progressive loss of vision, mental and motorExpand
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Genetic diversity of canine olfactory receptors
BackgroundEvolution has resulted in large repertoires of olfactory receptor (OR) genes, forming the largest gene families in mammalian genomes. Knowledge of the genetic diversity of olfactoryExpand
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Facilitating genome navigation: survey sequencing and dense radiation-hybrid gene mapping
Accurate and comprehensive sequence coverage for large genomes has been restricted to only a few species of specific interest. Lower sequence coverage (survey sequencing) of related species can yieldExpand
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